Chromosomal abnormalities in Ph- cells of patients on imatinib

被引：17

作者：

McMullin, MF ^{[1
]}

Humphreys, M ^{[1
]}

Byrne, J ^{[1
]}

Russell, NH ^{[1
]}

Cuthbert, RJ ^{[1
]}

O'Dwyer, ME ^{[1
]}

机构：

[1] Belfast City Hosp, Belfast BT9 7AB, Antrim, North Ireland

来源：

BLOOD | 2003年 / 102卷 / 07期

关键词：

D O I：

10.1182/blood-2003-06-1943

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2700 / 2701

页数：2

共 7 条

[1] Clonal Ph-negative hematopoiesis in CML after therapy with imatinib mesylate is frequently characterized by trisomy 8 [J].

Andersen, MK ;

Pedersen-Bjorgaard, J ;

Kjeldsen, L ;

Dufva, IH ;

Brondum-Nielsen, K .

LEUKEMIA, 2002, 16 (07) :1390-1393

[2] Emergence of clonal cytogenetic abnormalities in Ph- cells in some CML patients in cytogenetic remission to imatinib but restoration of polyclonal hematopoiesis in the majority [J].

Bumm, T ;

Müller, C ;

Al-Ali, HK ;

Krohn, K ;

Shepherd, P ;

Schmidt, E ;

Leiblein, S ;

Franke, C ;

Hennig, E ;

Friedrich, T ;

Krahl, R ;

Niederwieser, D ;

Deininger, MWN .

BLOOD, 2003, 101 (05) :1941-1949

[3] Inhibition of c-kit receptor tyrosine kinase activity by STI 571, a selective tyrosine kinase inhibitor [J].

Heinrich, MC ;

Griffith, DJ ;

Druker, BJ ;

Wait, CL ;

Ott, KA ;

Zigler, AJ .

BLOOD, 2000, 96 (03) :925-932

[4] c-kit ligand and flt3 ligand:: Stem/progenitor cell factors with overlapping yet distinct activities [J].

Lyman, SD ;

Jacobsen, SEW .

BLOOD, 1998, 91 (04) :1101-1134

[5] Imatinib compared with interferon and low-dose cytarabine for newly diagnosed chronic-phase chronic myeloid leukemia [J].

O'Brien, SG ;

Guilhot, F ;

Larson, RA ;

Gathmann, I ;

Baccarani, M ;

Cervantes, F ;

Cornelissen, JJ ;

Fischer, T ;

Hochhaus, A ;

Hughes, T ;

Lechner, K ;

Nielsen, JL ;

Rousselot, P ;

Reiffers, J ;

Saglio, G ;

Shepherd, J ;

Simonsson, B ;

Gratwohl, A ;

Goldman, JM ;

Kantarjian, H ;

Taylor, K ;

Verhoef, G ;

Bolton, AE ;

Capdeville, R ;

Druker, BJ ;

Durrant, S ;

Schwarer, A ;

Joske, D ;

Seymour, J ;

Grigg, A ;

Ma, D ;

Arthur, C ;

Bradstock, K ;

Joshua, D ;

Louwagie, A ;

Martiat, P ;

Straetmans, N ;

Bosly, A ;

Shustik, C ;

Lipton, J ;

Forrest, D ;

Walker, I ;

Roy, DC ;

Rubinger, M ;

Bence-Bruckler, I ;

Kovacs, M ;

Turner, AR ;

Birgens, H ;

Bjerrum, O ;

Facon, T .

NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (11) :994-1004

[6] Demonstration of Philadelphia chromosome negative abnormal clones in patients with chronic myelogenous leukemia during major cytogenetic responses induced by imatinib mesylate [J].

O'Dwyer, ME ;

Gatter, KM ;

Loriaux, M ;

Druker, BJ ;

Olson, SB ;

Magenis, RE ;

Lawce, H ;

Mauro, MJ ;

Maziarz, RT ;

Braziel, RM .

LEUKEMIA, 2003, 17 (03) :481-487

[7] Regulation of cell death by the Abl tyrosine kinase [J].

Wang, JYJ .

ONCOGENE, 2000, 19 (49) :5643-5650

← 1 →