Inappropriate use of naloxone in cancer patients with pain

被引：20

作者：

Manfredi, PL

Ribeiro, S

Chandler, SW

Payne, R

机构：

[1] UNIV TEXAS,MD ANDERSON CANCER CTR,DEPT NEUROONCOL,SECT PAIN & SYMPTONM MANAGEMENT,HOUSTON,TX 77030

[2] UNIV TEXAS,MD ANDERSON CANCER CTR,DIV PHARM,HOUSTON,TX 77030

来源：

JOURNAL OF PAIN AND SYMPTOM MANAGEMENT | 1996年 / 11卷 / 02期

关键词：

naloxone; opioid; overdose; cancer sedation; confusion encephalopathy; coma;

D O I：

10.1016/0885-3924(95)00150-6

中图分类号：

R19 [保健组织与事业（卫生事业管理）];

学科分类号：

摘要：

Opioid overdose is rarely the primary cause of altered mental status in cancer patients receiving opioid therapy. The inappropriate administration of naloxone to reverse an abnormal mental status can cause severe withdrawal symptoms and pain. To illustrate this problem, we report the case of a patient inappropriately treated with naloxone and the results of a retrospective review of the medical records of 15 consecutive patients with cancer treated with naloxone in the emergency department over a 5-month period. We offer guidelines for a more thoughtful approach to the management of patients with cancer who present with encephalopathy.

引用

页码：131 / 134

页数：4