Randomised controlled trial of novel, simple, and well supervised weight reducing diets in outpatients

Objectives To investigate the contribution of novelty and simplicity to compliance with a low energy diet among obese outpatients. Design Three arm randomised trial for 16 weeks. Setting NHS hospital obesity clinic. Subjects 45 patients aged over 17 years with a body mass index > 27 who were not diabetic, pregnant, or lactating. Interventions Conventional 3.4 MJ diet (control), isoenergetic novel diet of milk only, or milk plus one designated food daily. Follow up visit every 4 weeks, Main outcome measure Weight loss. Results Mean weight loss (kg) after 16 weeks on control, milk only, and milk plus diets was 1.7 (95% confidence interval - 0.3 to 3.7), 9.4 (5.9 to 12.9), and 7.0 (2.7 to 11.3) respectively, Weight loss on the novel diets was significantly greater than on the control diet. Conclusions Dietary treatment can achieve as much weight loss in obese outpatients over 16 weeks as has been reported for the most successful drug treatment, but compliance with the prescribed diet is poor unless the diet is novel and simple.