Drug release from pH and ionic strength responsive poly(acrylic acid) grafted poly(vinylidenefluoride) membrane bags in vitro

被引：32

作者：

Järvinen, K ^{[1
]}

Åkerman, S

Svarfvar, B

Tarvainen, T

Viinikka, P

Paronen, P

机构：

[1] Univ Kuopio, Dept Pharmaceut, FIN-70211 Kuopio, Finland

[2] Abo Akad Univ, Dept Polymer Technol, Abo, Finland

[3] Helsinki Univ Technol, Phys Chem & Electrochem Lab, FIN-02150 Espoo, Finland

来源：

PHARMACEUTICAL RESEARCH | 1998年 / 15卷 / 05期

关键词：

responsive porous polymer membrane; poly(acrylic acid); pH and ionic strength sensitivity; drug release;

D O I：

10.1023/A:1011995725320

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

[No abstract available]

引用

页码：802 / 805

页数：4

共 15 条

[1] Transport of drugs across porous ion exchange membranes [J].

Akerman, S ;

Viinikka, P ;

Svarfvar, B ;

Jarvinen, K ;

Kontturi, K ;

Nasman, J ;

Urtti, A ;

Paronen, P .

JOURNAL OF CONTROLLED RELEASE, 1998, 50 (1-3) :153-166

[2] The influence of buffer species and strength on diltiazem HCl release from beads coated with the aqueous cationic polymer dispersions, eudragit RS, RL 30D [J].

Bodmeier, R ;

Guo, XD ;

Sarabia, RE ;

Skultety, PF .

PHARMACEUTICAL RESEARCH, 1996, 13 (01) :52-56

[3] Pulsatile local delivery of thrombolytic and antithrombotic agents using poly(N-isopropylacrylamide-co-methacrylic acid) hydrogels [J].

Brazel, CS ;

Peppas, NA .

JOURNAL OF CONTROLLED RELEASE, 1996, 39 (01) :57-64

[4] In vitro testing of a pulsatile delivery system and its in vivo application for immunisation against tetanus toxoid [J].

Cardamone, M ;

Lofthouse, SA ;

Lucas, JC ;

Lee, RP ;

ODonoghue, M ;

Brandon, MR .

JOURNAL OF CONTROLLED RELEASE, 1997, 47 (03) :205-219

[5] Binding of drugs to monoglyceride-based drug delivery systems [J].

Chang, CM ;

Bodmeier, R .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1997, 147 (02) :135-142

[6] INTERACTION BETWEEN CALCIUM, A MODEL DIVALENT-CATION, AND A RANGE OF POLY(ACRYLIC ACID) RESINS AS A FUNCTION OF SOLUTION PH [J].

CHARMAN, WN ;

CHRISTY, DP ;

GEUNIN, EP ;

MONKHOUSE, DC .

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY, 1991, 17 (02) :271-280

[7] Magnetically-responsive polymerized liposomes as potential oral delivery vehicles [J].

Chen, HM ;

Langer, R .

PHARMACEUTICAL RESEARCH, 1997, 14 (04) :537-540

[8]

HARADA J, 1992, ACS SYM SER, V480, pCH5

[9] Characterization of graft-modified porous polymer membranes [J].

Hautojarvi, J ;

Kontturi, K ;

Nasman, JH ;

Svarfvar, BL ;

Viinikka, P ;

Vuoristo, M .

INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH, 1996, 35 (02) :450-457

[10] Glucose-responsive gel from phenylborate polymer and poly(vinyl alcohol): Prompt response at physiological pH through the interaction of borate with amine group in the gel [J].

Hisamitsu, I ;

Kataoka, K ;

Okano, T ;

Sakurai, Y .

PHARMACEUTICAL RESEARCH, 1997, 14 (03) :289-293

← 1 2 →