Molecular cloning and expression of human chondroitin 6-sulfotransferase

被引：74

作者：

Fukuta, M

Kobayashi, Y

Uchimura, K

Kimata, K

Habuchi, O ^{[1
]}

机构：

[1] Aichi Univ Educ, Dept Life Sci, Aichi 4488542, Japan

[2] Aichi Med Univ, Inst Mol Sci Med, Aichi 48011, Japan

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1998年 / 1399卷 / 01期

关键词：

chondroitin sulfate; sulfotransferase; keratan sulfate; cloning;

D O I：

10.1016/S0167-4781(98)00089-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 [生物化学与分子生物学]; 081704 [应用化学];

摘要：

Using cDNA of chick chondroitin 6-sulfotransferase (C6ST), human C6ST cDNA has been isolated. The amino acid sequence of human C6ST displayed 74% identity to chick C6ST. The major difference in amino acid sequence between chick C6ST and human C6ST was the presence of a unique hydrophilic domain in human C6ST. A 7.8-kb message of C6ST was expressed ubiquitously in various human adult tissues, indicating a rather diverse function of C6ST. (C) 1998 Elsevier Science B.V. All rights reserved.

引用

页码：57 / 61

页数：5

共 18 条

[1]

ARUFFO A, 1991, CURRENT PROTOCOLS S, V17

[2]

MOLECULAR-CLONING AND EXPRESSION OF CHICK CHONDROCYTE CHONDROITIN 6-SULFOTRANSFERASE [J].