Kinase-phosphatase competition regulates Bacillus subtilis development

被引:85
作者
Perego, M [1 ]
机构
[1] Scripps Res Inst, Div Cellular Biol, Dept Mol & Expt Med, La Jolla, CA 92037 USA
关键词
D O I
10.1016/S0966-842X(98)01350-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The major regulator of sporulation initiation in Bacillus subtilis is the phosphorelay, a multicomponent signal transduction system. A myriad of signals, both positive and negative, from the environment, cell cycle and metabolism is received and interpreted by the phosphorelay and integrated through the opposing activity of protein kinases and protein aspartate phosphatases to create an extremely sophisticated regulatory network.
引用
收藏
页码:366 / 370
页数:5
相关论文
共 41 条
  • [1] THE SPOIIJ GENE, WHICH REGULATES EARLY DEVELOPMENTAL STEPS IN BACILLUS-SUBTILIS, BELONGS TO A CLASS OF ENVIRONMENTALLY RESPONSIVE GENES
    ANTONIEWSKI, C
    SAVELLI, B
    STRAGIER, P
    [J]. JOURNAL OF BACTERIOLOGY, 1990, 172 (01) : 86 - 93
  • [2] The Bacillus subtilis response regulator SpoOA stimulates transcription of the spoIIG operon through modification of RNA polymerase promoter complexes
    Bird, TH
    Grimsley, JK
    Hoch, JA
    Spiegelman, GB
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 1996, 256 (03) : 436 - 448
  • [3] Oligomerization of the phosphatase CheZ upon interaction with the phosphorylated form of CheY - The signal protein of bacterial chemotaxis
    Blat, Y
    Eisenbach, M
    [J]. JOURNAL OF BIOLOGICAL CHEMISTRY, 1996, 271 (02) : 1226 - 1231
  • [4] The complete genome sequence of Escherichia coli K-12
    Blattner, FR
    Plunkett, G
    Bloch, CA
    Perna, NT
    Burland, V
    Riley, M
    ColladoVides, J
    Glasner, JD
    Rode, CK
    Mayhew, GF
    Gregor, J
    Davis, NW
    Kirkpatrick, HA
    Goeden, MA
    Rose, DJ
    Mau, B
    Shao, Y
    [J]. SCIENCE, 1997, 277 (5331) : 1453 - +
  • [5] INITIATION OF SPORULATION IN BACILLUS-SUBTILIS IS CONTROLLED BY A MULTICOMPONENT PHOSPHORELAY
    BURBULYS, D
    TRACH, KA
    HOCH, JA
    [J]. CELL, 1991, 64 (03) : 545 - 552
  • [6] CHARBONNEAU H, 1992, ANNU REV CELL BIOL, V8, P463, DOI 10.1146/annurev.cellbio.8.1.463
  • [7] KapB is a lipoprotein required for KinB signal transduction and activation of the phosphorelay to sporulation in Bacillus subtilis
    Dartois, V
    Djavakhishvili, T
    Hoch, JA
    [J]. MOLECULAR MICROBIOLOGY, 1997, 26 (05) : 1097 - 1108
  • [8] 2-COMPONENT REGULATORS AND GENETIC COMPETENCE IN BACILLUS-SUBTILIS
    DUBNAU, D
    HAHN, J
    ROGGIANI, M
    PIAZZA, F
    WEINRAUCH, Y
    [J]. RESEARCH IN MICROBIOLOGY, 1994, 145 (5-6) : 403 - 411
  • [9] Cell-cell communication in gram-positive bacteria
    Dunny, GM
    Leonard, BAB
    [J]. ANNUAL REVIEW OF MICROBIOLOGY, 1997, 51 : 527 - 564
  • [10] WHOLE-GENOME RANDOM SEQUENCING AND ASSEMBLY OF HAEMOPHILUS-INFLUENZAE RD
    FLEISCHMANN, RD
    ADAMS, MD
    WHITE, O
    CLAYTON, RA
    KIRKNESS, EF
    KERLAVAGE, AR
    BULT, CJ
    TOMB, JF
    DOUGHERTY, BA
    MERRICK, JM
    MCKENNEY, K
    SUTTON, G
    FITZHUGH, W
    FIELDS, C
    GOCAYNE, JD
    SCOTT, J
    SHIRLEY, R
    LIU, LI
    GLODEK, A
    KELLEY, JM
    WEIDMAN, JF
    PHILLIPS, CA
    SPRIGGS, T
    HEDBLOM, E
    COTTON, MD
    UTTERBACK, TR
    HANNA, MC
    NGUYEN, DT
    SAUDEK, DM
    BRANDON, RC
    FINE, LD
    FRITCHMAN, JL
    FUHRMANN, JL
    GEOGHAGEN, NSM
    GNEHM, CL
    MCDONALD, LA
    SMALL, KV
    FRASER, CM
    SMITH, HO
    VENTER, JC
    [J]. SCIENCE, 1995, 269 (5223) : 496 - 512