New trends in instrumental design for surface plasmon resonance-based biosensors

被引:251
作者
Abbas, Abdennour [1 ]
Linman, Matthew J. [1 ]
Cheng, Quan [1 ]
机构
[1] Univ Calif Riverside, Dept Chem, Riverside, CA 92521 USA
基金
美国国家科学基金会;
关键词
Surface plasmon resonance; SPR imaging; Optical sensor; Biochip design; Biosensor; Label-free detection; NEGATIVE-INDEX METAMATERIAL; ATOMIC-FORCE MICROSCOPY; ENHANCED SENSITIVITY; PROTEIN INTERACTIONS; IMAGING DETECTION; SPR BIOSENSOR; SENSOR; ARRAYS; WAVE; EXCITATION;
D O I
10.1016/j.bios.2010.09.030
中图分类号
Q6 [生物物理学];
学科分类号
071011 [生物物理学];
摘要
Surface plasmon resonance (SPR)-based biosensing is one of the most advanced label free, real time detection technologies. Numerous research groups with divergent scientific backgrounds have investigated the application of SPR biosensors and studied the fundamental aspects of surface plasmon polaritons that led to new, related instrumentation. As a result, this field continues to be at the forefront of evolving sensing technology. This review emphasizes the new developments in the field of SPR-related instrumentation including optical platforms, chips design, nanoscale approach and new materials. The current tendencies in SPR-based biosensing are identified and the future direction of SPR biosensor technology is broadly discussed. (C) 2010 Elsevier B.V. All rights reserved.
引用
收藏
页码:1815 / 1824
页数:10
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