Natural products - a simple model to explain chemical diversity

被引:323
作者
Firn, RD [1 ]
Jones, CG
机构
[1] Univ York, Dept Biol, York YO10 5DD, N Yorkshire, England
[2] Inst Ecosyst Studies, New York, NY USA
关键词
D O I
10.1039/b208815k
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A simple evolutionary model is presented which explains why organisms produce so many. natural products, why so many have low biological activity, why enzymes involved in natural product synthesis have the properties, they do and why natural product metabolism is shaped as it is.
引用
收藏
页码:382 / 391
页数:10
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