Robertsonian translocations in wheat arise by centric misdivision of univalents at anaphase I and rejoining of broken centromeres during interkinesis of meiosis II

被引：76

作者：

Friebe, B ^{[1
]}

Zhang, P

Linc, G

Gill, BS

机构：

[1] Kansas State Univ, Dept Plant Pathol, Throckmorton Plant Sci Ctr 4024, Wheat Genet Resource Ctr, Manhattan, KS 66506 USA

[2] Hungarian Acad Sci, Agr Res Inst, H-1051 Budapest, Hungary

来源：

CYTOGENETIC AND GENOME RESEARCH | 2005年 / 109卷 / 1-3期

关键词：

D O I：

10.1159/000082412

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

The mechanism of origin of Robertsonian translocations was investigated in plants monosomic for chromosome 1A of wheat and 1H(t) of Elymus trachycaulus by GISH. Chromosomes 1A and 1H(t) stayed univalent in all metaphase I cells analyzed, suggesting that Robertsonian translocations do not originate from meiotic recombination in centromeric regions with shared DNA sequence homology. At ana-/telophase I, the 1H(t) and 1A univalents underwent either chromosome or chromatid segregation and misdivided in 6 - 7% of the pollen mother cells. None of the ana-/telophases I analyzed had Robertsonian translocations, which were only observed in 2% of the "half tetrads" at ana-/telophase II. The frequency of Robertsonian translocations observed at ana-/telophase II corresponds well with the number of Robertsonian translocations ( 1 - 4%) detected in progenies derived from plants monosomic for group-1 chromosomes of wheat (1A, 1B, and 1D) and 1H(t) of E. trachycaulus. Our data suggest that Robertsonian translocations arise from centric misdivision of univalents at ana-/telophase I, followed by segregation of the derived telocentric chromosomes to the same nucleus, and fusion of the broken ends during the ensuing interkinesis. Copyright (C) 2005 S. Karger AG, Basel.

引用

页码：293 / 297

页数：5

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