Skin disorders in patients transplanted in childhood

被引:17
作者
Fortina, AB
Piaserico, S
Alaibac, M
Caforio, ALP
Brandolisio, L
Zacchello, G
Zanon, GF
Zancan, L
Peserico, A
机构
[1] Univ Padua, Dept Pediat, Dermatol Unit, I-35128 Padua, Italy
[2] Univ Padua, Dept Dermatol, I-35128 Padua, Italy
[3] Univ Padua, Dept Cardiol, I-35128 Padua, Italy
关键词
cancer; immunosuppressive drugs; infection; organ transplantation; pediatric; skin;
D O I
10.1111/j.1432-2277.2004.00069.x
中图分类号
R61 [外科手术学];
学科分类号
摘要
Only few data are available on skin disorders in pediatric organ transplant recipients. In order to describe the whole range of dermatological diseases in a population of pediatric organ transplant recipients, we studied a group of 217 consecutive organ transplant recipients (168 kidney, 29 heart, 19 liver, one lung) aged < 18 years at transplantation followed at a single center. A total of 193 patients showed at least one skin disorder; 149 had more than one skin disease. The most common skin infections were warts (24.4%), pityriasis versicolor (20.7%), folliculitis (12.9%), intertrigo (6.5%); the most common drug side effects were hypertrichosis (69.6%), steroid acne (39.6%), gingival hyperplasia (29%) and severe xerosis (20.7%). Two patients (0.9%) developed nonmelanoma skin cancer. Our study summarizes the main skin complications in patients transplanted in childhood and underlines the necessity of regular dermatologic surveillance of these patients.
引用
收藏
页码:360 / 365
页数:6
相关论文
共 8 条
[1]
Skin cancer in organ transplant recipients: Epidemiology, pathogenesis, and management [J].
Berg, D ;
Otley, CC .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2002, 47 (01) :1-17
[2]
Caforio ALP, 2000, CIRCULATION, V102, P222
[3]
Skin diseases in children with organ transplants [J].
Euvrard, S ;
Kanitakis, J ;
Cochat, P ;
Cambazard, F ;
Claudy, A .
JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2001, 44 (06) :932-939
[4]
Medical progress - Skin cancers after organ transplantation [J].
Euvrard, S ;
Kanitakis, J ;
Claudy, A .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 348 (17) :1681-1691
[5]
CUTANEOUS LESIONS ASSOCIATED WITH CYCLOSPORINE THERAPY IN PEDIATRIC RENAL-TRANSPLANT RECIPIENTS [J].
HALPERT, E ;
TUNNESSEN, WW ;
FIVUSH, B ;
CASE, B .
JOURNAL OF PEDIATRICS, 1991, 119 (03) :489-491
[6]
CUTANEOUS AND ORAL LESIONS IN 32 CHILDREN AFTER RENAL-TRANSPLANTATION [J].
MENNI, S ;
BERETTA, D ;
PICCINNO, R ;
GHIO, L .
PEDIATRIC DERMATOLOGY, 1991, 8 (03) :194-198
[7]
DE-NOVO MALIGNANCY IN PEDIATRIC ORGAN TRANSPLANT RECIPIENTS [J].
PENN, I .
JOURNAL OF PEDIATRIC SURGERY, 1994, 29 (02) :221-228
[8]
Skin diseases following organ transplantation - Risk factors and new therapeutic approaches [J].
Stockfleth, E ;
Ulrich, C ;
Meyer, T ;
Arndt, R ;
Christophers, E .
TRANSPLANTATION PROCEEDINGS, 2001, 33 (1-2) :1848-1853