Asymmetrical distribution of Neisseria miniature insertion sequence DNA repeats among pathogenic and nonpathogenic Neisseria strains

被引:18
作者
De Gregorio, E [1 ]
Abrescia, C [1 ]
Carlomagno, MS [1 ]
Di Nocera, PP [1 ]
机构
[1] Univ Naples, Dipartimento Biol & Patol Cellulare & Mol, I-80131 Naples, Italy
关键词
D O I
10.1128/IAI.71.7.4217-4221.2003
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Neisseria miniature insertion sequences (nemis) are miniature DNA insertion sequences found in Neisseria species. Out of 57 elements closely flanking cellular genes analyzed by PCR, most were conserved in Neisseria meningitidis but not in N. lactamica strains. Since mRNAs spanning nemis are processed by RNase III at hairpins formed by element termini, gene sets could selectively be regulated in meningococci at the posttranscriptional level.
引用
收藏
页码:4217 / 4221
页数:5
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