Synthesis and structure elucidation of a new potent sandalwood-oil substitute

被引：41

作者：

Bajgrowicz, JA ^{[1
]}

Frank, I

Fráter, G

Hennig, M

机构：

[1] Givaudan Roure Res Ltd, CH-8600 Dubendorf, Switzerland

[2] F Hoffmann La Roche & Co Ltd, Pharma Res, CH-4070 Basel, Switzerland

来源：

HELVETICA CHIMICA ACTA | 1998年 / 81卷 / 07期

关键词：

D O I：

10.1002/hlca.19980810545

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New derivatives of campholenaldehyde (=2-(2,2,3-trimethylcyclopent-3-enyl)ethanal) bearing two cyclopropane moieties were synthesized, and the structure of the stereoisomer responsible for its exceptionally strong, diffusive. and natural sandalwood-oil scent, ((1S,2S)-1-methyl-2-{[(1S,3R,5R)-1,2,2-trimethylbicyclo[3.1.0]hex-3-yl]methyl}cyclopropyl)methanol (13a), was elucidated.

引用

页码：1349 / 1358

页数：10

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