Indium tribromide:: a highly effective catalyst for the addition of trimethylsilyl cyanide to α-hetero-substituted ketones

被引：83

作者：

Bandini, M ^{[1
]}

Cozzi, PG ^{[1
]}

Melchiorre, P ^{[1
]}

Umani-Ronchi, A ^{[1
]}

机构：

[1] Univ Bologna, Dipartimento Chim G Ciamician, I-40126 Bologna, Italy

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 16期

关键词：

catalysis; cyanohydrins; indium; ketones;

D O I：

10.1016/S0040-4039(01)00368-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The catalytic addition of trimethylsilyl cyanide (TMSCN) to a large variety of hetero-substituted ketones promoted by anhydrous InBr3 has been studied. The low catalytic loading (0.1-1 mol%) and the mild experimental conditions required represent the key features of this novel catalytic system. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：3041 / 3043

页数：3

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