Suppressive effect of Lactobacillus gasseri OLL 2716 (LG21) on Helicobacter pylori infection in humans

被引:204
作者
Sakamoto, I
Igarashi, M
Kimura, K
Takagi, A
Miwa, T
Koga, Y [1 ]
机构
[1] Tokai Univ, Sch Med, Dept Infect Dis, Isehara, Kanagawa 2591193, Japan
[2] Tokai Univ, Sch Med, Dept Internal Med, Isehara, Kanagawa 2591193, Japan
[3] Meiji Milk Prod Co Ltd, Food Funct Res Inst, Higashimurayama, Tokyo 1898530, Japan
关键词
D O I
10.1093/jac/47.5.709
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
To examine the efficacy of Lactobacillus gasseri OLL2716 (LG21) as a probiotic for Helicobacter pylori in humans, 31 subjects infected with the bacterium ingested yogurt containing LG21 daily for an 8 week period. The [C-13]urea breath test and assays of serum pepsinogens revealed a significant improvement following LG21 treatment. LG21 was thus determined to be effective in both suppressing H. pylori and reducing gastric mucosal inflammation.
引用
收藏
页码:709 / 710
页数:2
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