Guanine oxidation: NMR characterization of a dehydro-guanidinohydantoin residue generated by a 2e-oxidation of d(GpT)

被引：39

作者：

Chworos, A ^{[1
]}

Coppel, Y ^{[1
]}

Dubey, I ^{[1
]}

Pratviel, G ^{[1
]}

Meunier, B ^{[1
]}

机构：

[1] CNRS, Chim Coordinat Lab, F-31077 Toulouse 4, France

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 2001年 / 123卷 / 25期

关键词：

D O I：

10.1021/ja003945p

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The Mn-TMPyP/KHSO5 system was used to oxidize guanine contained within a dinucleoside monophosphate d(GpT). To identify the guanine oxidation product having a mass with 4 amu above the mass of guanine itself, this relatively unstable compound was reduced to a more stable one. The ESI/MS and NMR data allowed us to propose a dehydro-guanidinohydantoin structure for the (G+4) guanine oxidation product.

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页码：5867 / 5877

页数：11

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