Extracorporeal shock wave therapy in early osteonecrosis of the femoral head: prospective clinical study with long-term follow-up

被引:167
作者
Vulpiani, Maria Chiara [1 ]
Vetrano, Mario [1 ]
Trischitta, Donatella [1 ]
Scarcello, Laura [1 ]
Chizzi, Federica [1 ]
Argento, Giuseppe [2 ]
Saraceni, Vincenzo Maria [1 ]
Maffulli, Nicola [3 ]
Ferretti, Andrea [4 ,5 ]
机构
[1] Univ Roma La Sapienza, Sch Med, St Andrea Hosp, Phys Med & Rehabil Unit, I-00189 Rome, Italy
[2] Univ Roma La Sapienza, Sch Med, St Andrea Hosp, Dept Radiol, I-00189 Rome, Italy
[3] Mile End Hosp, Barts & London Sch Med & Dent, Ctr Sports & Exercise Med, London, England
[4] St Andrea Hosp, Univ Sch Med, Orthopaed Unit, Rome, Italy
[5] St Andrea Hosp, Univ Sch Med, Kirk Kilgour Sports Injury Ctr, Rome, Italy
关键词
Shock wave therapy; Avascular necrosis of femoral head; ESWT; AVNFH; Conservative treatment; PULSED ELECTROMAGNETIC-FIELDS; BONE; HIP; NECROSIS; RABBITS; VEGF;
D O I
10.1007/s00402-011-1444-9
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
100224 [整形外科学];
摘要
Introduction Extracorporeal shock wave therapy (ESWT) may exert benefecial effects in avascular necrosis of femoral head (AVNFH). Patients The current study evaluated the effectiveness of ESWT in reducing pain and in slowing down the progression of bone damage in 36 patients with unilateral AVNFH of stage Association Research Circulation Osseous (ARCO) I, II and III. At the beginning of the study, 10 hips were classified as stage I, 11 as stage II and 15 as stage III. Each treatment cycle included four sessions, with 2,400 impulses each administered at 0.50 mJ/mm(2), at 48-72 h intervals. Follow-up examinations were scheduled at 3, 6, 12 and then 24 months. Met hod Clinical assessments included assessment of pain scores, Harris Hip Scores and Roles and Maudsley score. Plain radiographs and magnetic resonances of the hip were used to evaluate the size of the lesion, the extent of collapse of subchondral bone, and degenerative changes of the hip joint. Results Patients from ARCO stage I group and stage II group achieved significantly better results than patients from ARCO stage III group at all follow-up time points (p < 0.005). During the follow-up period, 10 of the 15 stage III ARCO patients received an arthroplasty. ARCO stages I and II lesions were unchanged on radiographs and on magnetic resonance images. Conclusion ESWT in ARCO stages I and II may help to prevent progression of the area of avascular necrosis and manage pain.
引用
收藏
页码:499 / 508
页数:10
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