The neuroimmunology of multiple sclerosis

被引：22

作者：

Coyle, PK

机构：

[1] Department of Neurology, Health Sciences Center, SUNY at Stony Brook, Stony Brook

来源：

ADVANCES IN NEUROIMMUNOLOGY | 1996年 / 6卷 / 02期

关键词：

multiple sclerosis; EAE; neuroimmunology; demyelinating disease;

D O I：

10.1016/0960-5428(96)00013-7

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The aim of this clinical review is to highlight recent advances in immunology, as well as new information from selected other areas, which have led to a better appreciation of the neuroimmunologic mechanisms involved in Multiple sclerosis (MS). New data on immunopathology, the cytokine network, and the role of oligodendrocytes, lymphocytes, and endothelial cells in this disease, have produced novel therapeutic approaches. New information on clinical course and neuroimaging disease features, as well as the role of genetic factors and infectious agents, have also improved our understanding of the immune basis for MS.

引用

页码：143 / 154

页数：12

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