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The enigma of sepsis

被引：513
作者：
Riedemann, NC [1 ]
Guo, RF [1 ]
Ward, PA [1 ]
机构：
[1] Univ Michigan, Sch Med, Dept Pathol, Ann Arbor, MI 48109 USA
来源：
JOURNAL OF CLINICAL INVESTIGATION | 2003年 / 112卷 / 04期
关键词：
D O I：
10.1172/JCI200319523
中图分类号：
R-3 [医学研究方法]; R3 [基础医学];
学科分类号：
1001 ;
摘要：
Sepsis remains a serious cause of morbidity and mortality, and the pathophysiology of the disease is not clear. The definition of the clinical manifestations of sepsis is ever evolving. This review discusses the search for effective therapeutic interventions, hurdles in translational sepsis research, and new therapies in development in current clinical trials.
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页码：460 / 467
页数：8
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