p53 codon 72 polymorphism in cervical cancer patients and healthy women from Poland

被引：16

作者：

Dybikowska, A

Dettlaff, A

Konopa, K

Podhajska, A

机构：

[1] Univ Gdansk, Intercollegiate Fac Biotechnol, Dept Biotechnol, PL-80822 Gdansk, Poland

[2] Med Univ Gdansk, Oncol & Radiotherapy Clin, Gdansk, Poland

来源：

ACTA BIOCHIMICA POLONICA | 2000年 / 47卷 / 04期

关键词：

cervical carcinoma; p53; gene; codon; 72; polymorphism;

D O I：

10.18388/abp.2000_3970

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A polymorphism at codon 72 of gene p53 results in the presence of either arginine or proline at this position. We investigated the distribution of p53 codon 72 polymorphism in cervical cancer patients and a control group of healthy women from Poland. Our results do not confirm the hypothesis that the p53 codon polymorphism could play a role as a factor for squamous carcinoma of the cervix.

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页码：1179 / 1182

页数：4

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