Mycobacterium tuberculosis infection in patients with cancer, the role of 18-fluorodeoxyglucose positron emission tomography for diagnosis and monitoring treatment response

被引：51

作者：

Hofmeyr, Ann

Lau, W. F. Eddie

Slavin, Monica A.

机构：

[1] Peter MacCallum Canc Ctr, Dept Infect Dis, Melbourne, Vic, Australia

[2] Peter MacCallum Canc Ctr, Ctr Mol Imaging, Melbourne, Vic, Australia

[3] Univ Melbourne, Dept Med Radiol, Melbourne, Vic, Australia

[4] Royal Melbourne Hosp, Ctr Clin Res Excellence Infect Dis, Melbourne, Vic, Australia

来源：

TUBERCULOSIS | 2007年 / 87卷 / 05期

关键词：

tuberculosis; treatment; malignancy; positron emission tomography; interferon-gamma;

D O I：

10.1016/j.tube.2007.05.013

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 [免疫学];

摘要：

Active tuberculosis (TB) infection including asymptomatic and extrapulmonary disease may be detected with 18-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT). This report highlights the promising role of FDG-PET/CT for evaluation of TB in high-risk, immunocompromised patients with cancer. PET/CT performed for cancer evaluation may detect asymptomatic infection and guide definitive diagnosis. It may also be a useful tool in the assessment of latent TB, to exclude active disease prior to treatment. PET/CT has potential for monitoring response to anti-tuberculosis treatment. Metabolic response may indicate clinical response and guide duration of anti-microbial therapy. Crown Copyright (c) 2007 Published by Elsevier Ltd. All rights reserved.

引用

页码：459 / 463

页数：5

共 19 条

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