Synthesis of granulatimide bis-imide analogues

被引：60

作者：

Hénon, H

Messaoudi, S

Hugon, B

Anizon, F

Pfeiffer, B

Prudhomme, M ^{[1
]}

机构：

[1] Univ Clermont Ferrand, Lab SEESIB, CNRS, UMR 6504, F-63177 Aubiere, France

[2] Inst Rech Servier, Div Rech Cancerol, F-78290 Croissy Sur Seine, France

来源：

TETRAHEDRON | 2005年 / 61卷 / 23期

关键词：

granulatimide; pyridino[2,3-b]dipyrrolo[3,4-e : 3,4-g]indole-1,3,4,6-tetraone; dipyrrolo[3,4-a : 3,4-c]carbazole-1,3,4,6-tetraone; 7-azaindole;

D O I：

10.1016/j.tet.2005.03.101

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The synthesis of dipyrrolo[3,4-a:3,4-c]carbazole-1,3,4.6-tetraones, structurally related to granulatimide is reported. These compounds can be considered as granulatimide analogues in which a maleimide heterocycle replaces the imidazole moiety. The synthesis of pyridino[2,3-b]dipyrrolo[3,4-e:3,4-g]indole-1,3,4,6-tetraones is also reported. In these compounds, a 7-azaindole unit replaces the indole moiety present in the granulatimide and isogranulatimide structures. (c) 2005 Elsevier Ltd. All rights reserved.

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页码：5599 / 5614

页数：16

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