Measures of disease activity and damage in SLE

被引：33

作者：

Urowitz, MB ^{[1
]}

Gladman, DD ^{[1
]}

机构：

[1] Toronto Hosp, Western Div, Ctr Prognosis Studies Rheumat Dis, Toronto, ON M5T 2S8, Canada

来源：

BAILLIERES CLINICAL RHEUMATOLOGY | 1998年 / 12卷 / 03期

关键词：

systemic lupus erythematosus; pathogenesis; disease assessment; CNS disease; renal disease; pregnancy; therapy and complications;

D O I：

10.1016/S0950-3579(98)80027-7

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Criteria for the classification of systemic lupus erythematosus (SLE) are not sufficient to describe the degree of disease activity. Several instruments to assess disease activity have been developed. This chapter reviews the derivation, validation, and clinical application of current disease activity measures in SLE, as well as comparison among them. As patients with lupus survive longer, the sequelae of the disease activity and its therapy are becoming more common. The derivation and validation of the single, generally accepted SLICC/ACR damage index is also discussed.

引用

页码：405 / 413

页数：9

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