Bilateral pallidal stimulation for cervical dystonia - An optimal paradigm from our experiences

被引:17
作者
Goto, S [1 ]
Mita, S
Ushio, Y
机构
[1] Kumamoto Univ, Sch Med, Dept Neurosurg, Kumamoto 8608556, Japan
[2] Kumamoto Univ, Sch Med, Dept Neurol, Kumamoto 8608556, Japan
关键词
cervical dystonia; deep brain stimulation; globus pallidus; stereotaxy;
D O I
10.1159/000070835
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
We sought to identify optimal paradigms of bilateral globus pallidus; internus (GPi) stimulation in 3 subsequent patients with severe cervical dystonia. At low frequency stimulation (50-60 Hz) with wide pulse width (500 mus) and high amplitude (4.5-8.0 V), we observed immediate and consistent improvement of dystonia and dystonia-associated pain. Stimulation of the posteroventral portion of the GPi led to pronounced alleviation of dystonia; stimulation of the anterodorsal portion or at the dorsal border of the GPi resulted in significant worsening of symptoms. The therapeutic benefit obtained by using the optimal stimulation parameters continues and has lasted for at least 1 year in each patient. Copyright (C) 2002 S. Karger AG, Basel.
引用
收藏
页码:221 / 227
页数:7
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