Fugitive inks for direct-write assembly of three-dimensional microvascular networks

被引:173
作者
Therriault, D
Shepherd, RF
White, SR
Lewis, JA
机构
[1] Univ Illinois, Frederick Seitz Mat Res Lab, Dept Mat Sci & Engn, NSF,Ctr Directed Assembly Nanostruct, Urbana, IL 61801 USA
[2] Univ Illinois, Adv Chem Syst Grp, Beckman Inst Adv Sci & Technol, Dept Aerosp Engn, Urbana, IL 61801 USA
[3] Ecole Polytech, Dept Mech Engn, Montreal, PQ H3C 3A7, Canada
关键词
D O I
10.1002/adma.200400481
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Direct-write assembly of three-dimensional (3D) scaffolds that retain their shape during fabrication and subsequent infiltration with an epoxy matrix are made possible by a new fugitive ink based on a binary mixture of a microcrystalline wax and a lower molecular weight organic compound. Removal of the ink creates a 3D network of interconnected microchannels within the matrix (see Figure).
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页码:395 / +
页数:6
相关论文
共 26 条
[1]   Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping [J].
Anderson, JR ;
Chiu, DT ;
Jackman, RJ ;
Cherniavskaya, O ;
McDonald, JC ;
Wu, HK ;
Whitesides, SH ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 2000, 72 (14) :3158-3164
[2]   Microfluidic tectonics: A comprehensive construction platform for microfluidic systems [J].
Beebe, DJ ;
Moore, JS ;
Yu, Q ;
Liu, RH ;
Kraft, ML ;
Jo, BH ;
Devadoss, C .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2000, 97 (25) :13488-13493
[3]   Functional hydrogel structures for autonomous flow control inside microfluidic channels [J].
Beebe, DJ ;
Moore, JS ;
Bauer, JM ;
Yu, Q ;
Liu, RH ;
Devadoss, C ;
Jo, BH .
NATURE, 2000, 404 (6778) :588-+
[4]  
Cesarano J., 2000, US Patent Patent, Patent No. [US6027326A, 6027326, 6027326A]
[5]   An integrated fluorescence detection system in poly(dimethylsiloxane) for microfluidic applications [J].
Chabinyc, ML ;
Chiu, DT ;
McDonald, JC ;
Stroock, AD ;
Christian, JF ;
Karger, AM ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 2001, 73 (18) :4491-4498
[6]   A microfabricated device for sizing and sorting DNA molecules [J].
Chou, HP ;
Spence, C ;
Scherer, A ;
Quake, S .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (01) :11-13
[7]   Generation of gradients having complex shapes using microfluidic networks [J].
Dertinger, SKW ;
Chiu, DT ;
Jeon, NL ;
Whitesides, GM .
ANALYTICAL CHEMISTRY, 2001, 73 (06) :1240-1246
[8]   Three-dimensional micro-channel fabrication in polydimethylsiloxane (PDMS) elastomer [J].
Jo, BH ;
Van Lerberghe, LM ;
Motsegood, KM ;
Beebe, DJ .
JOURNAL OF MICROELECTROMECHANICAL SYSTEMS, 2000, 9 (01) :76-81
[9]   Quantitative analysis of molecular interaction in a microfluidic channel: The T-sensor [J].
Kamholz, AE ;
Weigl, BH ;
Finlayson, BA ;
Yager, P .
ANALYTICAL CHEMISTRY, 1999, 71 (23) :5340-5347
[10]   Nanoparticle inks for directed assembly of three-dimensional periodic structures [J].
Li, Q ;
Lewis, JA .
ADVANCED MATERIALS, 2003, 15 (19) :1639-+