Predictors of Mitral Valve Repair: Clinical and Surgeon Factors

被引:252
作者
Bolling, Steven F. [1 ]
Li, Shuang
O'Brien, Sean M.
Brennan, J. Matthew
Prager, Richard L.
Gammie, James S.
机构
[1] Univ Michigan Hosp, Sect Cardiac Surg, Cardiovasc Ctr 5144, Ann Arbor, MI 48109 USA
关键词
HOSPITAL VOLUME; CARDIAC-SURGERY; MORTALITY; SOCIETY; REGURGITATION; DETERMINANTS; ASSOCIATION; OPERATION; OUTCOMES; DISEASE;
D O I
10.1016/j.athoracsur.2010.07.062
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background. Mitral valve repair is acknowledged as desirable and superior to replacement for virtually all mitral pathology. Utilizing The Society of Thoracic Surgeons (STS) Adult Cardiac Surgery Database (ACSD), a multivariable model was created that included patient clinical characteristics and surgeon-specific mitral volume to predict the likelihood of mitral valve repair. Methods. Between January 2005 and December 2007, 28,507 patients undergoing isolated mitral valve surgery (with or without tricuspid valve surgery, with or without atrial fibrillation surgery) by 1,088 surgeons at 639 hospitals in the STS ACSD were identified. Patient characteristics independently associated with mitral valve repair were identified using a generalized estimating equations logistic regression model. Observed mitral valve repair rates were plotted against surgeon-specific annual mitral volume, and predicted probabilities of mitral repair by surgeon volume were calculated after adjusting for patient baseline covariates. Results. On average, patients undergoing mitral valve surgery were 62 years old, with 51% female and 82% Caucasian. Among surgeons performing mitral procedures, the mean rate of mitral valve repair was 41% (range, 0% to 100%) and the median number of mitral valve operations per year was 5 (range, 1 to 166). Several patient characteristics were independently associated with a decreased odds of mitral repair (versus replacement), including mitral stenosis (odds ratio 0.09; 95% confidence interval: 0.08 to 0.11) and active endocarditis (odds ratio 0.21; 95% confidence interval: 0.17 to 0.25). While substantial variability in repair rates was observed among low-volume surgeons, increased surgeon-level mitral volume was independently associated with an increased probability of mitral repair. Conclusions. This analysis demonstrates marked variability in the frequency of mitral valve repair, and the influence of both patient-and surgeon-level factors on the likelihood of mitral valve repair. Increasing surgeon-specific annual mitral valve volume is associated with a higher probability of mitral repair. Identification of these predictors of mitral valve repair creates substantial opportunity for quality improvement in patient outcomes in mitral valve surgery, potentially through education, adoption of best practices, and improved mitral repair enabling technology. (Ann Thorac Surg 2010;90:1904-12) (C) 2010 by The Society of Thoracic Surgeons
引用
收藏
页码:1904 / 1912
页数:9
相关论文
共 32 条
[1]   Seeking a higher standard for degenerative mitral valve repair: Begin with etiology [J].
Adams, David H. ;
Anyanwu, Ani C. .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2008, 136 (03) :551-556
[2]   VALVE DISEASE Asymptomatic mitral regurgitation: does surgery save lives? [J].
Adams, David H. ;
Anyanwu, Anelechi C. .
NATURE REVIEWS CARDIOLOGY, 2009, 6 (05) :330-332
[3]   Failure of Guideline Adherence for Intervention in Patients With Severe Mitral Regurgitation [J].
Bach, David S. ;
Awais, Mazen ;
Gurm, Hitinder S. ;
Kohnstamm, Sarah .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (09) :860-865
[4]   Surgeon volume and operative mortality in the United States [J].
Birkmeyer, JD ;
Stukel, TA ;
Siewers, AE ;
Goodney, PP ;
Wennberg, DE ;
Lucas, FL .
NEW ENGLAND JOURNAL OF MEDICINE, 2003, 349 (22) :2117-2127
[5]   Hospital volume and surgical mortality in the United States. [J].
Birkmeyer, JD ;
Siewers, AE ;
Finlayson, EVA ;
Stukel, TA ;
Lucas, FL ;
Batista, I ;
Welch, HG ;
Wennberg, DE .
NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (15) :1128-1137
[6]   Guidelines for the management of patients with valvular heart disease - Executive summary - A report of the American College of Cardiology American Heart Association task force on practice guidelines (committee on management of patients with valvular heart disease) [J].
Bonow, RO ;
Carabello, B ;
de Leon, AC ;
Edmunds, LH ;
Fedderly, BJ ;
Freed, MD ;
Gaasch, WH ;
McKay, CR ;
Nishimura, RA ;
O'Gara, PT ;
O'Rourke, RA ;
Rahimtoola, SH ;
Ritchie, JL ;
Cheitlin, MD ;
Eagle, KA ;
Gardner, TJ ;
Garson, A ;
Gibbons, RJ ;
Russell, RO ;
Ryan, TJ ;
Smith, SC .
CIRCULATION, 1998, 98 (18) :1949-1984
[7]   Mitral repair best practice: proposed standards [J].
Bridgewater, B. ;
Hooper, T. ;
Munsch, C. ;
Hunter, S. ;
von Oppell, U. ;
Livesey, S. ;
Keogh, B. ;
Wells, F. ;
Patrick, M. ;
Kneeshaw, J. ;
Chambers, J. ;
Masani, N. ;
Ray, S. .
HEART, 2006, 92 (07) :939-944
[8]  
Chauvaud S, 2001, CIRCULATION, V104, pI12
[9]   Late outcomes of mitral valve repair for floppy valves: Implications for asymptomatic patients [J].
David, TE ;
Ivanov, J ;
Armstrong, S ;
Rakowski, H .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2003, 125 (05) :1143-1152
[10]   Quantitative determinants of the outcome of asymptomatic mitral regurgitation [J].
Enriquez-Sarano, M ;
Avierinos, JF ;
Messika-Zeitoun, D ;
Detaint, D ;
Capps, M ;
Nkomo, V ;
Scott, C ;
Schaff, HV ;
Tajik, AJ .
NEW ENGLAND JOURNAL OF MEDICINE, 2005, 352 (09) :875-883