Tenascins: regulation and putative functions during pathological stress

被引：436

作者：

Chiquet-Ehrismann, R

Chiquet, M

机构：

[1] Friedrich Miescher Inst, Novartis Res Fdn, CH-4058 Basel, Switzerland

[2] Univ Bern, ITI, Res Inst Dent & Skeletal Biol, Bern, Switzerland

来源：

JOURNAL OF PATHOLOGY | 2003年 / 200卷 / 04期

关键词：

tenascin; cancer; tumour; inflammation; extracellular matrix; cell adhesion; anti-adhesive; mechanical stress;

D O I：

10.1002/path.1415

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In this review, we discuss the structure and function of the extracellular matrix protein family of tenascins with emphasis on their involvement in human pathologies. The article is divided into the following sections: Introduction: the tenascin family of extracellular matrix proteins; Structural roles: tenascin-X deficiency and Ehlers-Danlos syndrome; Tenascins as modulators of cell adhesion, migration, and growth; Role of tenascin-C in inflammation; Regulation of tenascins by mechanical stress: implications for wound healing and regeneration; Association of tenascin-C with cancer: antibodies as diagnostic and therapeutic tools; Conclusion and perspectives. Copyright (C) 2003 John Wiley Sons, Ltd.

引用

收藏

页码：488 / 499

页数：12

相关论文

共 186 条

[1]

Adams M, 2002, CANCER RES, V62, P3289

[2] Inflammation and structural changes in the airways of patients with atopic and nonatopic asthma [J].

Amin, K ;

Lúdvíksdóttir, D ;

Janson, C ;

Nettelbladt, O ;

Björnsson, E ;

Roomans, GM ;

Boman, G ;

Sevéus, L ;

Venge, P .

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE, 2000, 162 (06) :2295-2301

[3] Relationship between inflammatory cells and structural changes in the lungs of asymptomatic and never smokers:: a biopsy study [J].

Amin, K ;

Ekberg-Jansson, A ;

Löfdahl, CG ;

Venge, P .

THORAX, 2003, 58 (02) :135-142

[4]

Angelov DN, 1998, J NEUROSCI, V18, P6218

[5] PHASE-I STUDIES OF TREATMENT OF MALIGNANT GLIOMAS AND NEOPLASTIC MENINGITIS WITH I-131 RADIOLABELED MONOCLONAL-ANTIBODIES ANTI-TENASCIN 81C6 AND ANTI-CHONDROITIN PROTEOGLYCAN SULFATE ME1-14 F(AB')(2) - A PRELIMINARY-REPORT [J].

BIGNER, DD ;

BROWN, M ;

COLEMAN, RE ;

FRIEDMAN, AH ;

FRIEDMAN, HS ;

MCLENDON, RE ;

BIGNER, SH ;

ZHAO, XG ;

WIKSTRAND, CJ ;

PEGRAM, CN ;

KERBY, T ;

ZALUTSKY, MR .

JOURNAL OF NEURO-ONCOLOGY, 1995, 24 (01) :109-122

[6] Iodine-131-labeled antitenascin monoclonal antibody 81C6 treatment of patients with recurrent malignant gliomas: Phase I trial results [J].

Bigner, DD ;

Brown, MT ;

Friedman, AH ;

Coleman, RE ;

Akabani, G ;

Friedman, HS ;

Thorstad, WL ;

McLendon, RE ;

Bigner, SH ;

Zhao, XG ;

Pegram, CN ;

Wikstrand, CJ ;

Herndon, JE ;

Vick, NA ;

Paleologos, N ;

Cokgor, I ;

Provenzale, JM ;

Zalutsky, MR .

JOURNAL OF CLINICAL ONCOLOGY, 1998, 16 (06) :2202-2212

[7] Towards defining roles and relationships for tenascin-C and TGFβ-1 in the normal and neoplastic urinary bladder [J].

Booth, C ;

Harnden, P ;

Selby, PJ ;

Southgate, J .

JOURNAL OF PATHOLOGY, 2002, 198 (03) :359-368

[8] EXPRESSION OF DIFFERENT TENASCIN ISOFORMS IN NORMAL, HYPERPLASTIC AND NEOPLASTIC HUMAN BREAST TISSUES [J].

BORSI, L ;

CARNEMOLLA, B ;

NICOLO, G ;

SPINA, B ;

TANARA, G ;

ZARDI, L .

INTERNATIONAL JOURNAL OF CANCER, 1992, 52 (05) :688-692

[9] PREVENTION OF GASTRULATION BUT NOT NEURULATION BY ANTIBODIES TO FIBRONECTIN IN AMPHIBIAN EMBRYOS [J].

BOUCAUT, JC ;

DARRIBERE, T ;

BOULEKBACHE, H ;

THIERY, JP .

NATURE, 1984, 307 (5949) :364-367

[10]

BOURDON MA, 1983, CANCER RES, V43, P2796

← 1 2 3 4 5 6 7 8 9 10 →