Estimating the Burden of 2009 Pandemic Influenza A (H1N1) in the United States (April 2009-April 2010)

被引：315

作者：

Shrestha, Sundar S. ^{[1
]}

Swerdlow, David L. ^{[2
]}

Borse, Rebekah H. ^{[3
]}

Prabhu, Vimalanand S. ^{[4
]}

Finelli, Lyn ^{[5
]}

Atkins, Charisma Y. ^{[3
]}

Owusu-Edusei, Kwame ^{[6
]}

Bell, Beth ^{[2
]}

Mead, Paul S. ^{[7
]}

Biggerstaff, Matthew ^{[5
]}

Brammer, Lynnette ^{[5
]}

Davidson, Heidi ^{[5
]}

Jernigan, Daniel ^{[5
]}

Jhung, Michael A. ^{[5
]}

Kamimoto, Laurie A. ^{[5
]}

Merlin, Toby L. ^{[8
]}

Nowell, Mackenzie ^{[5
]}

Redd, Stephen C. ^{[8
]}

Reed, Carrie ^{[5
]}

Schuchat, Anne ^{[2
]}

Meltzer, Martin I. ^{[3
]}

机构：

[1] Ctr Dis Control & Prevent, Div Diabet Translat, Atlanta, GA USA

[2] Ctr Dis Control & Prevent, Natl Ctr Immunizat & Resp Dis, Off Director, Atlanta, GA USA

[3] Ctr Dis Control & Prevent, Div Preparedness & Emerging Infect, Atlanta, GA USA

[4] Ctr Dis Control & Prevent, Div Global HIV AIDs, Atlanta, GA USA

[5] Ctr Dis Control & Prevent, Influenza Div, Atlanta, GA USA

[6] Ctr Dis Control & Prevent, Div Sexually Transmitted Dis Prevent, Atlanta, GA USA

[7] Ctr Dis Control & Prevent, Div Vector Borne Infect Dis, Atlanta, GA USA

[8] Ctr Dis Control & Prevent, Off Infect Dis, Atlanta, GA USA

来源：

CLINICAL INFECTIOUS DISEASES | 2011年 / 52卷

关键词：

D O I：

10.1093/cid/ciq012

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

To calculate the burden of 2009 pandemic influenza A (pH1N1) in the United States, we extrapolated from the Centers for Disease Control and Prevention's Emerging Infections Program laboratory-confirmed hospitalizations across the entire United States, and then corrected for underreporting. From 12 April 2009 to 10 April 2010, we estimate that approximately 60.8 million cases (range: 43.3-89.3 million), 274 304 hospitalizations (195 086-402 719), and 12 469 deaths (8868-18 306) occurred in the United States due to pH1N1. Eighty-seven percent of deaths occurred in those under 65 years of age with children and working adults having risks of hospitalization and death 4 to 7 times and 8 to 12 times greater, respectively, than estimates of impact due to seasonal influenza covering the years 1976-2001. In our study, adults 65 years of age or older were found to have rates of hospitalization and death that were up to 75% and 81%, respectively, lower than seasonal influenza. These results confirm the necessity of a concerted public health response to pH1N1.

引用

页码：S75 / S82

页数：8

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