Alkyl peroxyl radical-scavenging activity of catechins

被引：50

作者：

Nakao, M

Takio, S

Ono, K

机构：

[1] Kumamoto Univ, Grad Sch Sci & Technol, Dept Environm Sci, Kumamoto 860, Japan

[2] Kumamoto Univ, Fac Sci, Dept Sci Biol, Kumamoto 860, Japan

来源：

PHYTOCHEMISTRY | 1998年 / 49卷 / 08期

关键词：

alkyl peroxyl radical; antioxidant; bactericidal action; radical scavenger; catechins;

D O I：

10.1016/S0031-9422(98)00333-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Alkyl peroxyl radical (ROO.) generated from the reaction between 20 mM t-butyl hydroperoxide (t-BuOOH) and 200 mu M hematin could kill E. coli. The minimum concentrations of catechins sufficient to rescue the bacteria treated with ROO. were found to be 70 mu M for (-)-epicatechingallate, 100 mu M for (-)-epicatechin and 125 mu M for (+)-catechin. These values were comparable with the value of alpha-tocopherol, a typical ROO. scavenger. On the other hand, L-ascorbate and beta-carotene revealed about one tenth the scavenging activity of catechins. No scavenging activity was found for superoxide dismutase even at 86 mM. These facts indicate that catechins have high ROO. scavenging activity. (C) 1998 Elsevier Science Ltd. All rights reserved.

引用

页码：2379 / 2382

页数：4

共 19 条

[1] BACTERICIDAL ACTIVITY OF ALKYL PEROXYL RADICALS GENERATED BY HEME-IRON-CATALYZED DECOMPOSITION OF ORGANIC PEROXIDES [J].