Molecular pathogenesis of head and neck cancers

被引:15
作者
Singh, Bhuvanesh [1 ]
机构
[1] Mem Sloan Kettering Canc Ctr, Head & Neck Serv, Lab Epithelial Canc Biol, New York, NY 10065 USA
关键词
head and neck neoplasms; molecular biology; cancer pathogenesis;
D O I
10.1002/jso.21024
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Although individual genomic aberrations develop at specific time points in the progression axis, the precise role of these abnormalities in tumor progression and cancer behavior remain to be elucidated. This article will give an overview of the current knowledge on the molecular basis for the development of head and neck cancers.
引用
收藏
页码:634 / 639
页数:6
相关论文
共 87 条
[1]   Susceptibility to oral cancer by genetic polymorphisms at CYP1A1, GSTM1 and GSTT1 loci among Indians:: tobacco exposure as a risk modulator [J].
Anantharaman, Devasena ;
Chaubal, Pranay M. ;
Kannan, Sadhana ;
Bhisey, Rajani A. ;
Mahimkar, Manoj B. .
CARCINOGENESIS, 2007, 28 (07) :1455-1462
[2]  
[Anonymous], [No title captured]
[3]  
Armour B. S., 2005, Morbidity and Mortality Weekly Report, V54, P625
[4]   Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck [J].
Bonner, JA ;
Harari, PM ;
Giralt, J ;
Azarnia, N ;
Shin, DM ;
Cohen, RB ;
Jones, CU ;
Sur, R ;
Raben, D ;
Jassem, J ;
Ove, R ;
Kies, MS ;
Baselga, J ;
Youssoufian, H ;
Amellal, N ;
Rowinsky, EK ;
Ang, KK .
NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (06) :567-578
[5]  
Bova RJ, 1999, CLIN CANCER RES, V5, P2810
[6]   ASSOCIATION BETWEEN CIGARETTE-SMOKING AND MUTATION OF THE P53 GENE IN SQUAMOUS-CELL CARCINOMA OF THE HEAD AND NECK [J].
BRENNAN, JA ;
BOYLE, JO ;
KOCH, WM ;
GOODMAN, SN ;
HRUBAN, RH ;
EBY, YJ ;
COUCH, MJ ;
FORASTIERE, AA ;
SIDRANSKY, D .
NEW ENGLAND JOURNAL OF MEDICINE, 1995, 332 (11) :712-717
[7]   INFLUENCE OF CIGARETTE-SMOKING ON THE EFFICACY OF RADIATION-THERAPY IN HEAD AND NECK-CANCER [J].
BROWMAN, GP ;
WONG, G ;
HODSON, I ;
SATHYA, J ;
RUSSELL, R ;
MCALPINE, L ;
SKINGLEY, P ;
LEVINE, MN .
NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (03) :159-163
[8]  
Califano J, 1996, CANCER RES, V56, P2488
[9]   Cellular senescence: when bad things happen to good cells [J].
Campisi, Judith ;
di Fagagna, Fabrizio d'Adda .
NATURE REVIEWS MOLECULAR CELL BIOLOGY, 2007, 8 (09) :729-740
[10]   Case-control study of human papillomavirus and oropharyngeal cancer [J].
D'Souza, Gypsyamber ;
Kreimer, Aimee R. ;
Viscidi, Raphael ;
Pawlita, Michael ;
Fakhry, Carole ;
Koch, Wayne M. ;
Westra, William H. ;
Gillison, Maura L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 356 (19) :1944-1956