Antibodies against Candida: Potential therapeutics?

被引：36

作者：

Matthews, R ^{[1
]}

Burnie, J ^{[1
]}

机构：

[1] UNIV MANCHESTER, MANCHESTER ROYAL INFIRM, DEPT MED MICROBIOL, MANCHESTER M13 9WL, LANCS, ENGLAND

来源：

TRENDS IN MICROBIOLOGY | 1996年 / 4卷 / 09期

关键词：

D O I：

10.1016/0966-842X(96)10056-1

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For many years, there has been controversy over the role of antibodies in immunity to Candida, but recently specific antibodies to mannoproteins and hsp90 have been shown to be protective against murine candidiasis. Combined with technical advances in antibody engineering, this raises the possibility of harnessing such antibodies into a new range of therapeutics.

引用

页码：354 / 358

页数：5

共 41 条

[1]

AL-DOORY Y, 1970, Sabouraudia, V8, P41

[2] STRAIN DEPENDENCE OF ANTIBODY-MEDIATED PROTECTION IN MURINE SYSTEMIC CANDIDIASIS [J].

ASHMAN, RB ;

PAPADIMITRIOU, JM .

JOURNAL OF INFECTIOUS DISEASES, 1993, 168 (02) :511-513

[3]

BODEY GP, 1993, CANDIDIASIS, P207

[4] IMMUNOGENICITY AND ANTIGENICITY OF A PLASMODIUM-FALCIPARUM PROTEIN-FRACTION (90-110 KDA) ABLE TO PROTECT SQUIRREL-MONKEYS AGAINST ASEXUAL BLOOD STAGES [J].

BONNEFOY, S ;

GYSIN, J ;

BLISNICK, T ;

GUILLOTTE, M ;

CARCY, B ;

DASILVA, LP ;

MERCEREAUPUIJALON, O .

VACCINE, 1994, 12 (01) :32-40

[5]

Borrebaeck CA., 1995, ANTIBODY ENG

[6] SPECIFIC, HIGH-AFFINITY BINDING-SITES FOR HUMAN LUTEINIZING-HORMONE (HLH) AND HUMAN CHORIONIC-GONADOTROPIN (HCG) IN CANDIDA SPECIES [J].

BRAMLEY, TA ;

MENZIES, GS ;

WILLIAMS, RJ ;

ADAMS, DJ ;

KINSMAN, OS .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1990, 167 (03) :1050-1056

[7] STEROID-HORMONE REGULATION OF THE ACHLYA-AMBISEXUALIS 85-KILODALTON HEAT-SHOCK PROTEIN, A COMPONENT OF THE ACHLYA STEROID-RECEPTOR COMPLEX [J].

BRUNT, SA ;

RIEHL, R ;

SILVER, JC .

MOLECULAR AND CELLULAR BIOLOGY, 1990, 10 (01) :273-281

[8]

CALDERONE RA, 1991, MICROBIOL REV, V55, P1

[9]

Calderone Richard A., 1993, Trends in Microbiology, V1, P55, DOI 10.1016/0966-842X(93)90033-N

[10] ANTIBODY IMMUNITY AND INVASIVE FUNGAL-INFECTIONS [J].

CASADEVALL, A .

INFECTION AND IMMUNITY, 1995, 63 (11) :4211-4218

← 1 2 3 4 5 →