Synthesis of a fully functionalized protected C1-C11 fragment for the synthesis of the tedanolides

被引：38

作者：

Jung, ME ^{[1
]}

Lee, CP ^{[1
]}

机构：

[1] Univ Calif Los Angeles, Dept Chem & Biochem, Los Angeles, CA 90095 USA

来源：

ORGANIC LETTERS | 2001年 / 3卷 / 03期

关键词：

D O I：

10.1021/ol000329p

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

[GRAPHICS] The use of several non-aldol aldol processes allows one to prepare a fully functionalized and completely protected C1-C11 fragment that should be useful for the total synthesis of the tedanolides.

引用

页码：333 / 336

页数：4

共 28 条

[1] TI(O-I-PR)4-MEDIATED NUCLEOPHILIC OPENINGS OF 2,3-EPOXY ALCOHOLS - A MILD PROCEDURE FOR REGIOSELECTIVE RING-OPENING
CARON, M
SHARPLESS, KB
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1985, 50 (09) : 1557 - 1560
[2] A SELECTIVE AND EFFICIENT DEMESYLATION USING METHYLMAGNESIUM BROMIDE
COSSY, J
RANAIVOSATA, JL
BELLOSTA, V
WIETZKE, R
[J]. SYNTHETIC COMMUNICATIONS, 1995, 25 (20) : 3109 - 3112
[3] DAMICO DC, 1995, THESIS UCLA LOS ANGE
[4] TOTAL SYNTHESIS OF ELFAMYCINS - AURODOX AND EFROTOMYCIN .1. STRATEGY AND CONSTRUCTION OF KEY INTERMEDIATES
DOLLE, RE
NICOLAOU, KC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (06) : 1691 - 1694
[5] BIOACTIVE MARINE METABOLITES .35. CYTOTOXIC METABOLITES OF THE MARINE SPONGE MYCALE-ADHAERENS LAMBE
FUSETANI, N
SUGAWARA, T
MATSUNAGA, S
HIROTA, H
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1991, 56 (16) : 4971 - 4974
[6] HORITA K, 1989, CHEM PHARM BULL, V37, P1705
[7] Enantioselective total syntheses of the 5,11-methanomorphanthridine Amaryllidaceae alkaloids (-)-pancracine and (-)-coccinine
Jin, J
Weinreb, SM
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (08) : 2050 - 2051
[8] JOHNSON MR, 1979, TETRAHEDRON LETT, V20, P4343
[9] ENANTIOSPECIFIC SYNTHESIS OF ALL 4 DIASTEREOMERS OF 2-METHYL-3-((TRIALKYLSILYL)OXY)ALKANALS - FACILE PREPARATION OF ALDOLS BY NON-ALDOL CHEMISTRY
JUNG, ME
DAMICO, DC
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (25) : 12208 - 12209
[10] Stereoselective production of β-amino alcohols and β-thioacyl alcohols via an application of the non-aldol aldol process
Jung, ME
Sun, DQ
[J]. TETRAHEDRON LETTERS, 1999, 40 (48) : 8343 - 8346

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