Iridoids from Gardenia jasminoides

被引:32
作者
Ragasa, Consolacion Y.
Pimenta, Leslie Elline N.
Rideout, John A.
机构
[1] De La Salle Univ, Dept Chem, Manila 1004, Philippines
[2] De La Salle Univ, Ctr Nat Sci & Ecol Res, Manila 1004, Philippines
[3] Univ Cent Queensland, Sch Chem & Biomed Sci, Queensland 4701, Australia
关键词
Gardenia jasminoides ellis; rubiaceae; iridoids;
D O I
10.1080/14786410701589998
中图分类号
O69 [应用化学];
学科分类号
081704 [应用化学];
摘要
The dichloromethane extract of the air- dried flowers of Gardenia jasminoides Ellis. afforded a new iridoid natural product ( 1), and a diastereomeric mixture of two new iridoids ( 2a and 2b) in a 2 : 1 ratio. Their structures were elucidated by extensive 1D and 2D NMR spectroscopy. Antimicrobial tests on 1 indicated that it was moderately active against Candida albicans; slightly active against E. coli, Pseudomonas aeruginosa, Staphylococcus. aureus, and Trichophyton mentagrophytes; and inactive against Bacillus subtilis and Aspergillus niger.
引用
收藏
页码:1078 / 1084
页数:7
相关论文
共 6 条
[1]
SYNTHESIS OF A COREY LACTONE ANALOG FROM IRIDOID GLUCOSIDE AUCUBIN AND ITS UTILIZATION IN THE SYNTHESIS OF A NEW 12-EPI-PGF2-ALPHA MODIFIED AT C-11 [J].
BERNINI, R ;
DAVINI, E ;
IAVARONE, C ;
TROGOLO, C .
JOURNAL OF ORGANIC CHEMISTRY, 1986, 51 (24) :4600-4603
[2]
GUEVARA BQ, 1985, ACTA MANILANA
[3]
Quisumbing E, 1978, MED PLANTS PHILIPPIN, P553
[4]
SAWADA Y, 2002, GEKKAN FUDO KEMIKARU, V18, P60
[5]
WALLER GR, 1984, P OKLA ACAD SCI, V64, P49
[6]
WANG C, 1981, ZHONGCAOYAO, V12, P487