Does C-Reactive Protein Predict Recurrent Preeclampsia?

被引：21

作者：

Gammill, Hilary S. ^{[1
,2
]}

Powers, Robert W. ^{[1
,2
]}

Clifton, Rebecca G. ^{[3
]}

Van Dorsten, J. Peter ^{[4
]}

Klebanoff, Mark A. ^{[5
]}

Lindheimer, Marshall D. ^{[6
]}

Sibai, Baha ^{[7
]}

Landon, Mark B. ^{[8
]}

Miodovnik, Menachem ^{[9
]}

Dombrowski, Mitchell ^{[10
]}

机构：

[1] Univ Pittsburgh, Dept Obstet, Pittsburgh, PA USA

[2] Univ Pittsburgh, Dept Gynecol, Pittsburgh, PA USA

[3] George Washington Univ, Ctr Biostat, Washington, DC USA

[4] Med Univ S Carolina, Charleston, SC 29425 USA

[5] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Bethesda, MD USA

[6] Univ Chicago, Chicago, IL 60637 USA

[7] Univ Tennessee, Memphis, TN USA

[8] Ohio State Univ, Columbus, OH 43210 USA

[9] Univ Cincinnati, Cincinnati, OH USA

[10] Wayne State Univ, Detroit, MI USA

来源：

HYPERTENSION IN PREGNANCY | 2010年 / 29卷 / 04期

关键词：

Pregnancy; Preeclampsia; C Reactive protein Inflammation; Acute phase reaction; LONG-TERM MORTALITY; INFLAMMATORY CYTOKINES; NEUTROPHIL ACTIVATION; PREGNANT-WOMEN; POTENTIAL ROLE; RISK; PARAMETERS; HISTORY; DISEASE; MARKERS;

D O I：

10.3109/10641950903214633

中图分类号：

R71 [妇产科学];

学科分类号：

100211 [妇产科学];

摘要：

Objective Evaluate association of the inflammatory marker C reactive protein with recurrent preeclampsia Methods Serum samples collected longitudinally in women with previous preeclampsia from the Maternal Fetal Medicine Units Network trial of aspirin to prevent preeclampsia were assayed for CRP Results Of 255 women studied, 50 developed recurrence Baseline C reactive protein concentration was similar between women who did and did not recur After adjusting for confounders, neither elevated baseline C reactive protein nor its change over gestation was associated with recurrence Conclusion In this group of women with previous preeclampsia, neither baseline C reactive protein concentration nor change in concentration over gestation was associated with recurrent preeclampsia

引用

页码：399 / 409

页数：11

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