Nickel and the carbon cycle

被引:111
作者
Ragsdale, Stephen W. [1 ]
机构
[1] Univ Michigan, Dept Biol Chem, Ann Arbor, MI 48109 USA
关键词
acetogenesis; iron-sulfur; methanogenesis; CO2; fixation;
D O I
10.1016/j.jinorgbio.2007.07.014
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
This article, dedicated to Edward Stiefel, reviews three nickel enzymes that play important roles in the carbon cycle: CO dehydrogenase, acetyl-CoA synthase, and methyl-coenzyme M reductase. After a short discussion of the carbon cycle, the structures of the active centers of the proteins and their proposed mechanisms are discussed. A brief description of future research areas is presented for each enzyme system. A short perspective on future research on nickel enzymes ends this contribution. (C) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:1657 / 1666
页数:10
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