Poor school and cognitive functioning with silent cerebral infarcts and sickle cell disease

被引:198
作者
Schatz, J [1 ]
Brown, RT
Pascual, JM
Hsu, L
DeBaun, MR
机构
[1] Univ S Carolina, Dept Psychol, Columbia, SC 29208 USA
[2] Med Univ S Carolina, Dept Pediat, Charleston, SC 29425 USA
[3] Columbia Univ, Coll Phys & Surg, Div Pediat Neurol, New York, NY USA
[4] Emory Univ, Sch Med, Dept Pediat, Atlanta, GA USA
[5] Washington Univ, Sch Med, Dept Pediat, St Louis, MO 63110 USA
关键词
D O I
10.1212/WNL.56.8.1109
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
The authors evaluated education attainment and neuro-psychological deficits in children with sickle cell disease (SCD) and silent cerebral infarcts. Children with silent infarcts had twice the rate of school difficulties as children without infarcts. Eighty percent of silent infarct cases had clinically significant cognitive deficits, whereas 35% had deficits in academic skills. Children with silent cerebral infarcts show high rates of poor educational attainment, cognitive deficits, and frontal lobe injury. Poor school performance in SCD is one indicator of silent infarcts.
引用
收藏
页码:1109 / 1111
页数:3
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