PURPOSE: To demonstrate a successful repair of an intractable Descemet membrane detachment. METHODS: ease report. We used transcorneal mattress sutures ro fxate Descemet membrane to the cornea in combination with intracameral air injection. RESULT: This technique resulted in reattachment of Descemet membrane and a substantial visual acuity improvement after complete resolution of corneal edema. CONCLUSIONS: Surgical repair may be needed in cases of large Descemet membrane detachment. This technique provides an additional surgical alternative to repair intractable Descemet membrane detachment without causing excessive anterior chamber disruption; it may also prevent the need for a penetrating keratoplasty. (C) 1999 by Elsevier Science Inc. All rights reserved.