Risk factors and burden of osteoarthritis

被引：709

作者：

Palazzo, Clemence ^{[1
]}

Nguyen, Christelle ^{[1
]}

Lefevre-Colau, Marie-Martine ^{[1
]}

Rannou, Francois ^{[1
]}

Poiraudeau, Serge ^{[1
]}

机构：

[1] Univ Paris 05, PRES Sorbonne Paris Cite, Hop Cochin,AP HP,U1153,Inserm, Serv Reeduc & Readaptat Appareil Locomoteur & Pat, 27 Rue Faubourg St Jacques, F-75014 Paris, France

来源：

ANNALS OF PHYSICAL AND REHABILITATION MEDICINE | 2016年 / 59卷 / 03期

关键词：

Epidemiology; Osteoarthritis; Risk factors; Mortality; Disability; Prevalence; Burden; ANTERIOR CRUCIATE LIGAMENT; KNEE OSTEOARTHRITIS; CARDIOVASCULAR-DISEASE; HAND OSTEOARTHRITIS; RHEUMATIC CONDITIONS; SYMPTOMATIC HAND; OBESE-PATIENTS; GLOBAL BURDEN; ALL-CAUSE; VITAMIN-D;

D O I：

10.1016/j.rehab.2016.01.006

中图分类号：

R49 [康复医学];

学科分类号：

100232 [康复医学];

摘要：

Osteoarthritis (OA) is one of the most common joint disorders worldwide. Its prevalence is increasing because of the growing aging of the population in developed and developing countries as well as an increase in risk factors leading to OA, particularly obesity and a sedentary lifestyle. Risk factors of OA can be divided into person-level factors (age, gender, obesity, genetics and diet) and joint-level factors (injury, malalignment and abnormal loading of the joints) that interact in a complex manner. OA is the 11th cause of disability in the world. It is responsible for activity limitations, particularly walking, and affects participation and quality of life. Patients with OA are at greater risk of all-cause mortality, particularly for cardiovascular diseases, than the general population. This excess mortality is closely associated with disability level. Consequently, strategies to reduce burden through primary and secondary prevention programs are increasingly important. (C) 2016 Elsevier Masson SAS. All rights reserved.

引用

页码：134 / 138

页数：5

共 61 条

[1]

FACTORS ASSOCIATED WITH OSTEO-ARTHRITIS OF THE KNEE IN THE 1ST NATIONAL-HEALTH AND NUTRITION EXAMINATION SURVEY (HANES-I) - EVIDENCE FOR AN ASSOCIATION WITH OVERWEIGHT, RACE, AND PHYSICAL DEMANDS OF WORK [J].