Inactivation of human enterovirus 71 and coxsackie virus A16 and hand, foot, and mouth disease

被引：28

作者：

Kadurugamuwa, Jagath L. ^{[1
]}

Shaheen, Elias ^{[1
]}

机构：

[1] Clorox Serv Co, Pleasanton, CA 94588 USA

来源：

AMERICAN JOURNAL OF INFECTION CONTROL | 2011年 / 39卷 / 09期

关键词：

Disinfectant; sodium hypochlorite; bleach; biocide; nonenveloped viruses; SUSCEPTIBILITY; DISINFECTANTS;

D O I：

10.1016/j.ajic.2011.01.015

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

100235 [预防医学];

摘要：

Human enterovirus 71 (EV71) and coxsackievirus A16 (CVA16) are the two major etiological agents in major outbreaks of hand, foot, and mouth disease. Transmission of these viruses is facilitated by prolonged environmental survival and their resistance to biocides, and effective disinfection is crucial to interrupt the cycle of environmental spread. We tested the virucidal efficacy of sodium hypochlorite against both EV71 and CVA16, performed according to the Association of Official Analytical Chemists (AOAC) test criteria and methods approved by the US Environmental Protection Agency. Our results indicated the complete inactivation of infectivity of EV71 and CVA16 after a 5-minute exposure to 3120 ppm sodium hypochlorite.

引用

页码：788 / 789

页数：2

共 12 条

[1]

Significance of fomites in the spread of respiratory and enteric viral disease [J].