Cyclosporin A toxicity, growth factor (VEGF) and more:: vascular endothelial steps forward

被引:13
作者
Caramelo, C
Alvarez-Arroyo, V
Yagüe, S
Suzuki, Y
Castilla, A
Velasco, L
Gonzalez-Pacheco, FR
Tejedor, A
机构
[1] Univ Autonoma Madrid, Clin Concepc, Lab Nefrol & Hipertens, Madrid 28040, Spain
[2] Hosp Gen Gregorio Maranon, Inst Reina Sofia Invest Nefrol, Madrid, Spain
关键词
calcineurin; cyclosporin A; endothelial cells; toxicity; tubular cells; vascular endothelial growth factor;
D O I
10.1093/ndt/gfg516
中图分类号
R3 [基础医学]; R4 [临床医学];
学科分类号
1001 ; 1002 ; 100602 ;
摘要
引用
收藏
页码:285 / 288
页数:4
相关论文
共 29 条
[1]   Cyclophilin-mediated pathways in the effect of cyclosporin A on endothelial cells -: Role of vascular endothelial growth factor [J].
Alvarez-Arroyo, MV ;
Yagüe, S ;
Wenger, RM ;
Pereira, DS ;
Jiménez, S ;
González-Pacheco, FR ;
Castilla, MA ;
Deudero, JJP ;
Caramelo, C .
CIRCULATION RESEARCH, 2002, 91 (03) :202-209
[2]   Role of endogenous vascular endothelial growth factor in tubular cell protection against acute cyclosporine toxicity [J].
Arroyo, MVA ;
Suzuki, Y ;
Yagüe, S ;
Lorz, C ;
Jiménez, S ;
Soto, C ;
Barat, A ;
Belda, E ;
González-Pacheco, FR ;
Deudero, JJP ;
Castilla, MA ;
Egido, J ;
Ortiz, A ;
Caramelo, C .
TRANSPLANTATION, 2002, 74 (11) :1618-1624
[3]   Cyclosporine A up-regulates expression of matrix metalloproteinase 2 and vascular endothelial growth factor in rat heart [J].
Bianchi, R ;
Rodella, L ;
Rezzani, R .
INTERNATIONAL IMMUNOPHARMACOLOGY, 2003, 3 (03) :427-433
[4]   Role of vascular endothelial growth factor (VEGF) in endothelial cell protection against cytotoxic agents [J].
Castilla, MA ;
Caramelo, C ;
Gazapo, RM ;
Martín, O ;
González-Pacheco, FR ;
Tejedor, A ;
Bragado, R ;
Arroyo, MVA .
LIFE SCIENCES, 2000, 67 (09) :1003-1013
[5]   Peritubular capillary loss is associated with chronic tubulointerstitial injury in human kidney: Altered expression of vascular endothelial growth factor [J].
Choi, YJ ;
Chakraborty, S ;
Nguyen, V ;
Nguyen, C ;
Kim, BK ;
Shim, SI ;
Suki, WN ;
Truong, LD .
HUMAN PATHOLOGY, 2000, 31 (12) :1491-1497
[6]   Increased renal expression of vascular endothelial growth factor (VEGF) and its receptor VEGFR-2 in experimental diabetes [J].
Cooper, ME ;
Vranes, D ;
Youssef, S ;
Stacker, SA ;
Cox, AJ ;
Rizkalla, B ;
Casley, DJ ;
Bach, LA ;
Kelly, DJ ;
Gilbert, RE .
DIABETES, 1999, 48 (11) :2229-2239
[7]   Hypoxia and interleukin-1β stimulate vascular endothelial growth factor production in human proximal tubular cells [J].
El Awad, B ;
Kreft, B ;
Wolber, EM ;
Hellwig-Bürgel, T ;
Metzen, E ;
Fandrey, J ;
Jelkmann, W .
KIDNEY INTERNATIONAL, 2000, 58 (01) :43-50
[8]   Glomerular-specific alterations of VEGF-A expression lead to distinct congenital and acquired renal diseases [J].
Eremina, V ;
Sood, M ;
Haigh, J ;
Nagy, A ;
Lajoie, G ;
Ferrara, N ;
Gerber, HP ;
Kikkawa, Y ;
Miner, JH ;
Quaggin, SE .
JOURNAL OF CLINICAL INVESTIGATION, 2003, 111 (05) :707-716
[9]   The biology of VEGF and its receptors [J].
Ferrara, N ;
Gerber, HP ;
LeCouter, J .
NATURE MEDICINE, 2003, 9 (06) :669-676
[10]   MECHANISMS OF THE ENDOTHELIAL TOXICITY OF CYCLOSPORINE-A ROLE OF NITRIC-OXIDE, CGMP, AND CA2+ [J].
GALLEGO, MJ ;
VILLALON, ALG ;
FARRE, AJL ;
GARCIA, JL ;
GARRON, MP ;
CASADO, S ;
HERNANDO, L ;
CARAMELO, CA .
CIRCULATION RESEARCH, 1994, 74 (03) :477-484