Open radical cystectomy with lymphadenectomy remains the treatment of choice for invasive bladder cancer

被引:98
作者
Huang, George J. [1 ]
Stein, John P. [1 ]
机构
[1] Univ So Calif, Kenneth Norris Jr Comprehens Canc Ctr, Dept Urol, Keck Sch Med, Los Angeles, CA 90098 USA
关键词
laparoscopy; lymphadenectomy; radical cystectomy; transitional cell carcinoma; urinary diversion; urothelial tumor;
D O I
10.1097/MOU.0b013e3282dc95b5
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 [临床医学]; 100201 [内科学];
摘要
Purpose of review Radical cystectomy with an appropriate lymph node dissection and an appropriate form of urinary diversion is the standard treatment for muscle-invasive transitional cell carcinoma of the bladder. Optimal outcomes following radical cystectomy require an extended lymph node dissection, negative surgical margins, and a continent urinary diversion. There has been an increasing number of reports describing initial experiences with laparoscopic radical cystectomy. Recent findings Intermediate and long-term oncologic outcomes with laparoscopic radical cystectomy remain undefined, and appropriate lymph node dissections laparoscopically have not been uniformly performed. Furthermore, the long-term functional outcomes associated with laparoscopically performed urinary diversions also remain undefined. There appears to be a recent trend toward performing the urinary diversion portion of the procedure extracorporeally, after laparoscopic removal of the bladder. Some studies suggest a decrease in postoperative analgesic requirements and quicker recovery of bowel function in those undergoing laparoscopic radical cystectomy, but these observations have not been corroborated by others. Summary In the absence of long-term functional and oncologic outcome data, laparoscopic radical cystectomy should be considered an investigative technique, and potential candidates for this operation should be appropriately counseled.
引用
收藏
页码:369 / 375
页数:7
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