Inframolecular protonation studies of 5-deoxy-5,5-difluoro-myo-inositol-1,2,6-tris(phosphate)

被引：2

作者：

Ballereau, S ^{[1
]}

Schlewer, G ^{[1
]}

Spiess, B ^{[1
]}

机构：

[1] Fac Pharm, UPR 421 CNRS, Lab Pharmacochim Mol, F-67401 Illkirch Graffenstaden, France

来源：

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS | 1997年 / 128卷

关键词：

inositol-phosphates; protonation; micro-constants; P-31 NMR titration; NUCLEAR-MAGNETIC-RESONANCE;

D O I：

10.1080/10426509708031570

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The study investigates quantitatively the acid-base properties of 5-deoxy-5,5-difluoro-myo-inositol-1,2,6-tris(phosphate) at an inframolecular level by considering the microscopic protonation constants. By comparison with alpha-trinositol, its inositol parent compound, conclusions are drawn about the influence of an hydroxyl group vicinal to a phosphate group.

引用

页码：147 / 151

页数：5

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