Paraneoplastic and metastatic neurologic complications of Merkel cell carcinoma

被引：36

作者：

Eggers, SDZ

Salomao, DR

Dinapoli, RP

Vernino, S

机构：

[1] Mayo Clin, Dept Neurol, Rochester, MN 55905 USA

[2] Mayo Clin, Div Anat Pathol, Rochester, MN 55905 USA

来源：

MAYO CLINIC PROCEEDINGS | 2001年 / 76卷 / 03期

关键词：

D O I：

10.4065/76.3.327

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Merkel cell carcinoma is a rare primary cutaneous neuroendocrine tumor that is locally aggressive and frequently accompanied by distant metastases, Neurologic complications of Merkel cell carcinoma are rare. We describe a 69-year-old man who presented with Lambert-Eaton myasthenic syndrome and was found to have Merkel cell carcinoma. The paraneoplastic syndrome improved with initial treatment of the malignancy. He subsequently developed a solitary brain metastasis and died of leptomeningeal carcinomatosis.

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页码：327 / 330

页数：4

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