C-509T polymorphism in the TGFB1 gene promoter:: impact on Crohn's disease susceptibility and clinical course?

被引:24
作者
Schulte, CMS
Goebell, H
Röher, HD
Schulte, KM
机构
[1] Univ Essen, Dept Internal Med, Div Endocrinol, D-45122 Essen, Germany
[2] Univ Essen, Dept Internal Med, Div Gastroenterol, D-45122 Essen, Germany
[3] Univ Dusseldorf, Clin Gen Surg, D-40225 Dusseldorf, Germany
关键词
inflammatory bowel disease; Crohn's disease; fibrosis;
D O I
10.1007/s002510100309
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
[No abstract available]
引用
收藏
页码:178 / 182
页数:5
相关论文
共 27 条
[1]   TRANSFORMING GROWTH-FACTOR-BETA AS A PREDICTOR OF LIVER AND LUNG FIBROSIS AFTER AUTOLOGOUS BONE-MARROW TRANSPLANTATION FOR ADVANCED BREAST-CANCER [J].
ANSCHER, MS ;
PETERS, WP ;
REISENBICHLER, H ;
PETROS, WP ;
JIRTLE, RL .
NEW ENGLAND JOURNAL OF MEDICINE, 1993, 328 (22) :1592-1598
[2]   Genotypic variation in the transforming growth factor-β1 gene -: Association with transforming growth factor-pi production, fibrotic lung disease, and graft fibrosis after lung transplantation [J].
Awad, MR ;
El-Gamel, A ;
Hasleton, P ;
Turner, DM ;
Sinnott, PJ ;
Hutchinson, IV .
TRANSPLANTATION, 1998, 66 (08) :1014-1020
[3]   Expression of transforming growth factors alpha and beta in colonic mucosa in inflammatory bowel disease [J].
Babyatsky, MW ;
Rossiter, G ;
Podolsky, DK .
GASTROENTEROLOGY, 1996, 110 (04) :975-984
[4]   Growth factors in inflammatory bowel disease [J].
Beck, PL ;
Podolsky, DK .
INFLAMMATORY BOWEL DISEASES, 1999, 5 (01) :44-60
[5]  
BORDER WA, 1994, NEW ENGL J MED, V331, P1286
[6]   TGF-β and fibrosis [J].
Branton, MH ;
Kopp, JB .
MICROBES AND INFECTION, 1999, 1 (15) :1349-1365
[7]   Transforming growth factor-βs and their signaling receptors are coexpressed in Crohn's disease [J].
di Mola, FF ;
Friess, H ;
Scheuren, A ;
Di Sebastiano, P ;
Graber, H ;
Egger, B ;
Zimmermann, A ;
Korc, M ;
Büchler, MW .
ANNALS OF SURGERY, 1999, 229 (01) :67-75
[8]   CYTOKINE MODULATION OF INTESTINAL EPITHELIAL-CELL RESTITUTION - CENTRAL ROLE OF TRANSFORMING GROWTH-FACTOR-BETA [J].
DIGNASS, AU ;
PODOLSKY, DK .
GASTROENTEROLOGY, 1993, 105 (05) :1323-1332
[9]   Intestinal inflammation: a complex interplay of immune and nonimmune cell interactions [J].
Fiocchi, C .
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 1997, 273 (04) :G769-G775
[10]  
Friess H, 1998, Langenbecks Arch Chir Suppl Kongressbd, V115, P994