Androgen receptor in the ovary of postnatal bank vole females

被引:3
作者
Galas, J [1 ]
Slomczynska, M [1 ]
Kwasnik, A [1 ]
机构
[1] Jagiellonian Univ, Dept Anim Physiol, Lab Endocrinol & Tissue Culture, PL-30060 Krakow, Poland
来源
TRENDS IN COMPARATIVE ENDOCRINOLOGY AND NEUROBIOLOGY | 2005年 / 1040卷
关键词
bank vole; postnatal ovary; androgen receptor (AR);
D O I
10.1196/annals.1327.050
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 [生物化学与分子生物学]; 081704 [应用化学];
摘要
In this experiment, we investigated the influence of the photoperiod upon androgen receptor (AR) distribution and steroid concentrations in ovaries of 21-day-old bank vole females. Sections (6 mu m) were assayed immunohistochemically. ARs were localized in the nuclei of granulosa cells. The strongest immunoreaction was observed in primary and early antral follicles, and declined during follicular development. P-4, A, and E-2 contents were measured by RIAs in ovarian homogenates from animals kept in two photoperiods. Ovaries of animals kept in a long photoperiod (18:6 light:dark), which stimulates gonadal activity, contained more P-4 than those kept in a short one (6:18 light:dark). There was no difference in levels of A and E-2.
引用
收藏
页码:315 / 319
页数:5
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