Asymmetry in bridged binuclear metalloenzymes: Lessons for the chemist

被引：81

作者：

Belle, C ^{[1
]}

Pierre, JL ^{[1
]}

机构：

[1] Univ Grenoble 1, UMR CNRS 5616, LEDSS, F-38041 Grenoble, France

来源：

EUROPEAN JOURNAL OF INORGANIC CHEMISTRY | 2003年 / 23期

关键词：

unsymmetrical binuclear metalloenzymes superoxide dismutase; purple acid phosphatases; catechol oxidases; model complexes;

D O I：

10.1002/ejic.200300231

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

This microreview describes the structures, properties and mechanisms of three selected bimetallic enzymes: Cu-Zn superoxide dismutase (SOD), purple acid phosphatases (PAPs) and catechol oxidases (COs). The relevance of the unsymmetrical structures in the binucleating environment to the reaction mechanism and the respective roles of each metal center of these enzymes are discussed. Relevant model compounds are also considered. (C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003).

引用

页码：4137 / 4146

页数：10

共 67 条

[1]

Ackermann J, 2002, CHEM-EUR J, V8, P247, DOI 10.1002/1521-3765(20020104)8:1<247::AID-CHEM247>3.0.CO

[2]

2-P

[3]

Albedyhl S, 2002, EUR J INORG CHEM, P1400

[4]

Albedyhl S, 2001, EUR J INORG CHEM, P1457

[5] MECHANISM OF THE REACTION OF DIFFERENT PHOSPHATES WITH THE IRON(II)IRON(III) FORM OF PURPLE ACID-PHOSPHATASE FROM PORCINE UTERI (UTEROFERRIN) [J].

AQUINO, MAS ;

LIM, JS ;

SYKES, AG .

JOURNAL OF THE CHEMICAL SOCIETY-DALTON TRANSACTIONS, 1994, (04) :429-436

[6] SPECTROSCOPIC AND MAGNETIC STUDIES OF THE PURPLE ACID-PHOSPHATASE FROM BOVINE SPLEEN [J].

AVERILL, BA ;

DAVIS, JC ;

BURMAN, S ;

ZIRINO, T ;

SANDERSLOEHR, J ;

LOEHR, TM ;

SAGE, JT ;

DEBRUNNER, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1987, 109 (12) :3760-3767

[7] PROPERTIES OF THE FE(II)-FE(III) DERIVATIVE OF RED KIDNEY BEAN PURPLE PHOSPHATASE - EVIDENCE FOR A BINUCLEAR ZN-FE CENTER IN THE NATIVE ENZYME [J].

BECK, JL ;

DEJERSEY, J ;

ZERNER, B ;

HENDRICH, MP ;

DEBRUNNER, PG .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (10) :3317-3318

[8]

Beguin C, 1997, B SOC CHIM FR, V134, P635

[9] Dicopper(II) complexes of H-BPMP-type ligands:: pH-induced changes of redox, spectroscopic (19F NMR studies of fluorinated complexes), structural properties, and catecholase activities [J].

Belle, C ;

Beguin, C ;

Gautier-Luneau, I ;

Hamman, S ;

Philouze, C ;

Pierre, JL ;

Thomas, F ;

Torelli, S .

INORGANIC CHEMISTRY, 2002, 41 (03) :479-491

[10]

Belle C, 2002, EUR J INORG CHEM, P3087

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