Early left periventricular brain lesions induce right hemispheric organization of speech

被引:114
作者
Staudt, M
Grodd, W
Niemann, G
Wildgruber, D
Erb, M
Krägeloh-Mann, I
机构
[1] Univ Tubingen, Childrens Hosp, Dept Neuroradiol, Tubingen, Germany
[2] Univ Tubingen, Childrens Hosp, Radiol Clin, Tubingen, Germany
[3] Univ Tubingen, Childrens Hosp, Dept Pediat Neurol & Dev Med, Tubingen, Germany
关键词
D O I
10.1212/WNL.57.1.122
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Right-hemispheric organization of speech has been observed following early left-sided brain lesions involving the language cortex. The authors studied speech organization in hemiparetic patients with pre-and. perinatally acquired lesions in the left periventricular white matter using fMRI, and found that right-hemisphere activation correlated with left facial motor tract involvement. This suggests that the impairment of speech motor output from the left hemisphere plays an important role in this alteration of language representation.
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页码:122 / 125
页数:4
相关论文
共 10 条
[1]   Functional organization of activation patterns in children: Whole brain fMRI imaging during three different cognitive tasks [J].
Booth, JR ;
Macwhinney, B ;
Thulborn, KR ;
Sacco, K ;
Voyvodic, J ;
Feldman, HM .
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY, 1999, 23 (04) :669-682
[2]   Language cortex representation: Effect of developmental versus acquired pathology [J].
Duchowny, M ;
Jayakar, P ;
Harvey, AS ;
Resnick, T ;
Alvarez, L ;
Dean, P ;
Levin, B .
ANNALS OF NEUROLOGY, 1996, 40 (01) :31-38
[3]   Improvement of the acquisition of a large amount of MR images on a conventional whole body system [J].
Klose, U ;
Erb, M ;
Wildgruber, D ;
Müller, E ;
Grodd, W .
MAGNETIC RESONANCE IMAGING, 1999, 17 (03) :471-474
[4]   INTERHEMISPHERIC DISSOCIATION OF EXPRESSIVE AND RECEPTIVE LANGUAGE FUNCTIONS IN PATIENTS WITH COMPLEX-PARTIAL SEIZURES - AN AMOBARBITAL STUDY [J].
KURTHEN, M ;
HELMSTAEDTER, C ;
LINKE, DB ;
SOLYMOSI, L ;
ELGER, CE ;
SCHRAMM, J .
BRAIN AND LANGUAGE, 1992, 43 (04) :694-712
[5]   Functional MR evaluation of temporal and frontal language dominance compared with the Wada test [J].
Lehéricy, S ;
Cohen, L ;
Bazin, B ;
Samson, S ;
Giacomini, E ;
Rougetet, R ;
Hertz-Pannier, L ;
Le Bihan, D ;
Marsault, C ;
Baulac, M .
NEUROLOGY, 2000, 54 (08) :1625-1633
[6]  
Rasmussen T, 1977, Ann N Y Acad Sci, V299, P355, DOI 10.1111/j.1749-6632.1977.tb41921.x
[7]   Language dominance in neurologically normal and epilepsy subjects - A functional MRI study [J].
Springer, JA ;
Binder, JR ;
Hammeke, TA ;
Swanson, SJ ;
Frost, JA ;
Bellgowan, PSF ;
Brewer, CC ;
Perry, HM ;
Morris, GL ;
Mueller, WM .
BRAIN, 1999, 122 :2033-2045
[8]   The pyramidal tract in congenital hemiparesis:: Relationship between morphology and function in periventricular lesions [J].
Staudt, M ;
Niemann, G ;
Grodd, W ;
Krägeloh-Mann, I .
NEUROPEDIATRICS, 2000, 31 (05) :257-264
[9]  
VOLPE JJ, 1995, NEUROLOGY NEWBORN, P211
[10]   Functional lateralization of speech production at primary motor cortex: A fMRI study [J].
Wildgruber, D ;
Ackermann, H ;
Klose, U ;
Kardatzki, B ;
Grodd, W .
NEUROREPORT, 1996, 7 (15-17) :2791-2795