Macrolide resistance in Peptostreptococcus spp. mediated by ermTR:: Possible source of macrolide-lincosamide-streptogramin B resistance in Streptococcus pyogenes

被引：31

作者：

Reig, M ^{[1
]}

Galan, JC ^{[1
]}

Baquero, F ^{[1
]}

Perez-Diaz, JC ^{[1
]}

机构：

[1] Hosp Ramon y Cajal, Natl Inst Hlth INSALUD, Dept Microbiol, E-28034 Madrid, Spain

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2001年 / 45卷 / 02期

关键词：

D O I：

10.1128/AAC.45.2.630-632.2001

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Eighty percent (21 of 26) of macrolide-resistant Peptostreptococcus strains studied harbored the ermTR gene. This methyltransferase gene is also the most frequently found gene among macrolide-lincosamide-streptogramin B-resistant Streptococcus pyogenes strains. Transfer of the ermTR gene from Peptostreptococcus magnus to macrolide-susceptible S. pyogenes strains indicates that this resistance determinant may circulate among gram-positive aerobic and anaerobic species of the oropharyngeal bacterial flora.

引用

页码：630 / 632

页数：3

共 17 条

[1] CLONING AND SEQUENCE-ANALYSIS OF ERMQ, THE PREDOMINANT MACROLIDE-LINCOSAMIDE-STREPTOGRAMIN-B RESISTANCE GENE IN CLOSTRIDIUM-PERFRINGENS [J].

BERRYMAN, DI ;

LYRISTIS, M ;

ROOD, JI .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1994, 38 (05) :1041-1046

[2] Host range of the ermF rRNA methylase gene in bacteria of human and animal origin [J].

Chung, WSO ;

Werckenthin, C ;

Schwarz, S ;

Roberts, MC .

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 1999, 43 (01) :5-14

[3] Prevalence and mechanisms of macrolide resistance in clinical isolates of group A streptococci from Ontario, Canada [J].

De Azavedo, JCS ;

Yeung, RH ;

Bast, DJ ;

Duncan, CL ;

Borgia, SB ;

Low, DE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (09) :2144-2147

[4] Phenotypes and genotypes of erythromycin-resistant Streptococcus pyogenes strains in Italy and heterogeneity of inducibly resistant strains [J].

Giovanetti, E ;

Montanari, MP ;

Mingoia, M ;

Varaldo, PE .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (08) :1935-1940

[5] Erythromycin resistance genes in group A streptococci in Finland [J].

Kataja, J ;

Huovinen, P ;

Skurnik, M ;

Seppälä, H .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1999, 43 (01) :48-52

[6] Different erythromycin resistance mechanisms in group C and group G streptococci [J].

Kataja, J ;

Seppälä, H ;

Skurnik, M ;

Sarkkinen, H ;

Huovinen, P .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (06) :1493-1494

[7] CLONING AND ANALYSIS OF ERMG, A NEW MACROLIDE-LINCOSAMIDE-STREPTOGRAMIN-B RESISTANCE ELEMENT FROM BACILLUS-SPHAERICUS [J].

MONOD, M ;

MOHAN, S ;

DUBNAU, D .

JOURNAL OF BACTERIOLOGY, 1987, 169 (01) :340-350

[8]

*NAT COMM CLIN LAB, 1997, M11A4 NAT COMM CLIN

[9] Macrolide resistance phenotypes and mechanisms of resistance in Streptococcus pyogenes in La Rioja, Spain [J].

Portillo, A ;

Lantero, M ;

Gastañares, MJ ;

Ruiz-Larrea, F ;

Torres, C .

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS, 1999, 13 (02) :137-140

[10] COMPLETE NUCLEOTIDE-SEQUENCE AND TRANSCRIPTION OF ERMF, A MACROLIDE-LINCOSAMIDE-STREPTOGRAMIN B-RESISTANCE DETERMINANT FROM BACTEROIDES-FRAGILIS [J].

RASMUSSEN, JL ;

ODELSON, DA ;

MACRINA, FL .

JOURNAL OF BACTERIOLOGY, 1986, 168 (02) :523-533

← 1 2 →