Macrolide resistance in Peptostreptococcus spp. mediated by ermTR:: Possible source of macrolide-lincosamide-streptogramin B resistance in Streptococcus pyogenes

被引:31
作者
Reig, M [1 ]
Galan, JC [1 ]
Baquero, F [1 ]
Perez-Diaz, JC [1 ]
机构
[1] Hosp Ramon y Cajal, Natl Inst Hlth INSALUD, Dept Microbiol, E-28034 Madrid, Spain
关键词
D O I
10.1128/AAC.45.2.630-632.2001
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Eighty percent (21 of 26) of macrolide-resistant Peptostreptococcus strains studied harbored the ermTR gene. This methyltransferase gene is also the most frequently found gene among macrolide-lincosamide-streptogramin B-resistant Streptococcus pyogenes strains. Transfer of the ermTR gene from Peptostreptococcus magnus to macrolide-susceptible S. pyogenes strains indicates that this resistance determinant may circulate among gram-positive aerobic and anaerobic species of the oropharyngeal bacterial flora.
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收藏
页码:630 / 632
页数:3
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