Diagnosis and management of oncogenic cervical human papillomavirus infection

被引:28
作者
Gravitt, PE
Jamshidi, R
机构
[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD 21205 USA
[2] Johns Hopkins Bayview Med Ctr, Baltimore, MD 21224 USA
关键词
D O I
10.1016/j.idc.2005.03.008
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Because of the strong association of human papillormavirus (HPV) with invasive cervical cancer, research on HPV infection has targeted women. This article focuses primarily on the natural history and management of cervical HPV infection. A large body of epidemiologic research has allowed the development of a model of the natural history of HPV-associated cervical cancer whereby HPV is acquired by sexual transmission and is largely transient. Persistent infection with high-risk HPV confers a high risk for developing high-grade neoplasia and cancer.
引用
收藏
页码:439 / +
页数:22
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