New access to methyl formylcyclopropanecarboxylates via diethylaminotrimethylsilane mediated tandem nucleophilic reaction of aldehyde with methyl 2,3-dihalopropanoate

被引：12

作者：

Hagiwara, H

Komatsubara, N

Hoshi, T

Suzuki, T

Ando, M

机构：

[1] Niigata Univ, Grad Sch Sci & Technol, Niigata 9502181, Japan

[2] Niigata Univ, Fac Engn, Niigata 9502181, Japan

来源：

TETRAHEDRON LETTERS | 1999年 / 40卷 / 08期

关键词：

aldehydes; cyclopropanation; halo esters; Michael reactions;

D O I：

10.1016/S0040-4039(98)02668-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Formylcyclopropanecarboxylates have been synthesized by diethylaminotrimethylsilane mediated tandem conjugate addition-alkylation of aldehydes to methyl alpha-haloaclylate generated in situ from methyl 2,3-dihalopropanoate. (C) 1999 Elsevier Science Ltd. All rights reserved.

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页码：1523 / 1526

页数：4

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