Time scales for the formation of the most probable tertiary contacts in proteins with applications to cytochrome c

被引：58

作者：

Thirumalai, D ^{[1
]}

机构：

[1] Univ Maryland, Dept Chem & Biochem, College Pk, MD 20742 USA

[2] Univ Maryland, Inst Phys Sci & Technol, College Pk, MD 20742 USA

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 1999年 / 103卷 / 04期

关键词：

D O I：

10.1021/jp982362n

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A simple theory (practically without any adjustable parameter) for calculating the diffusion-limited rates of forming loops of arbitrary length in polypeptide chains is given. The time needed to form a tertiary contact between met80 and his18 in Cytochrome c is 40 mu s, which is in excellent agreement with experimental determinations.

引用

页码：608 / 610

页数：3

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